Brain-skull contact boundary conditions in an inverse computational deformation model.
Brain-skull contact boundary conditions in an inverse computational deformation model.
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DOI：
10.1016/j.media.2009.05.007
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发表时间：
2009-08
影响因子：
10.9
通讯作者：
Paulsen, Keith D.
中科院分区：
文献类型：
--
作者：
Ji, Songbai;Roberts, David W.;Hartov, Alex;Paulsen, Keith D.
关键词：
在手术室 (OR) 中模拟负载和边界条件下大脑运动的生物力学模型作为开颅神经外科手术期间大脑移位补偿的替代方案而受到关注。尽管在动态模拟中已经探讨了这些模型中脑-颅骨边界条件（BC）的重要性，但尚未在代表神经外科手术期间盛行的准静态大脑运动的模型中对其进行充分研究。在本研究中，我们通过将脑-颅骨接触 BC 合并到使用最速梯度下降 (SGD) 框架的变形场反演估计方案中来扩展脑-颅骨接触 BC 的应用。该技术允许实质表面运动垂直于颅骨，同时在开颅手术中保持无应力 BC，并最大限度地减少测量噪声的影响。该算法在五个临床病例中的应用（使用肿瘤边界生成的稀疏数据）证实了脑-颅骨 BC 在模型响应中的重要性。具体而言，结果表明，与不允许实质表面正常运动时获得的性能相比，接触 BC 增强了模型灵活性，并在肿瘤边界处实现了改进或相当的性能（恢复约 85% 的变形）。它还显着提高了开颅手术时的模型估计精度（平均 1.6 毫米），尤其是在正常运动较大时。该方法的重要性在于，当脑-颅骨接触影响变形场时，模型性能显着提高，但当接触不太重要并且更简单的 BC 就足够时，模型性能不会降低。该技术的计算成本目前平均为 3.9 分钟，但可以通过将迭代求解器应用于所涉及的线性方程组和/或通过对感兴趣区域中的网格进行局部细化来进一步降低计算成本。
Biomechanical models simulating brain motion under loading and boundary conditions in the operating room (OR) are gaining attention as alternatives for brain shift compensation during open cranial neurosurgeries. Although the significance of brain–skull boundary conditions (BCs) in these models has been explored in dynamic simulations, it has not been fully investigated in models representing the quasi-static brain motion that prevails during neurosurgery. In this study, we extend the application of a brain–skull contact BC by incorporating it into an inversion estimation scheme for the deformation field using the steepest gradient descent (SGD) framework. The technique allows parenchymal surface motion normal to the skull while maintaining stress-free BCs at the craniotomy and minimizing the effect of measurement noise. Application of the algorithm in five clinical cases using sparse data generated at the tumor boundary confirms the significance of brain–skull BCs in the model response. Specifically, the results demonstrate that the contact BC enhances model flexibility and achieves improved or comparable performance at the tumor boundary (recovering about 85% of the deformation) relative to that obtained when normal motion of the parenchymal surface is not allowed. It also significantly improves model estimation accuracy at the craniotomy (1.6 mm on average), especially when the normal motion is large. The importance of the method is that model performance significantly improves when brain–skull contact influences the deformation field but does not degrade when the contact is less critical and simpler BCs would suffice. The computational cost of the technique is currently 3.9 min on average, but may be further reduced by applying an iterative solver to the linear systems of equations involved and/or by local refinement of the mesh in regions of interest.
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影响因子：
10.6
作者：
Maurer, CR;Hill, DLG;Truwit, CL
通讯作者：
Truwit, CL
影响因子：
3.8
作者：
Ji, Songbai;Wu, Ziji;Paulsen, Keith D.
通讯作者：
Paulsen, Keith D.
影响因子：
4.8
作者：
Nimsky, C;Ganslandt, O;Fahlbusch, R
通讯作者：
Fahlbusch, R
DOI：
10.1109/34.121791
发表时间：
1992-02-01
影响因子：
23.6
作者：
BESL, PJ;MCKAY, ND
通讯作者：
MCKAY, ND
影响因子：
4.8
作者：
Hartov, Alex;Roberts, David W.;Paulsen, Keith D.
通讯作者：
Paulsen, Keith D.