Reproductive Biology and Endocrinology E-cadherin Expression and Bromodeoxyuridine Incorporation during Development of Ovarian Inclusion Cysts in Age-matched Breeder and Incessantly Ovulated Cd-1 Mice

Reproductive Biology and Endocrinology E-cadherin Expression and Bromodeoxyuridine Incorporation during Development of Ovarian Inclusion Cysts in Age-matched Breeder and Incessantly Ovulated Cd-1 Mice
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生殖生物学和内分泌学 年龄匹配的种小鼠和持续排卵的 Cd-1 小鼠卵巢包涵体囊肿发育过程中 E-钙粘蛋白的表达和溴脱氧尿苷的掺入

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发表时间:
2007
期刊:
影响因子:
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通讯作者:
H James
H James
中科院分区:
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文献类型:
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作者:
J. Fleming;James Mcquillan;Melanie J. Millier;C. Beaugié;V. Livingstone;J. F. E. Au;H James

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背景:连续排卵8个月的雌性CD-1/Swiss Webster小鼠和12个月的繁殖小鼠均出现类似浆液性囊腺瘤的卵巢包囊性囊肿。大多数囊肿表现为卵巢小管扩张,但高排卵数导致更多的皮质包涵囊肿。我们假设,比较相同年龄但一生总排卵数不同的动物的包涵性囊肿病理,可能使我们能够确定两种类型囊肿的区别特征。
Background: Female CD-1/Swiss Webster mice subjected to incessant ovulation for 8 months and 12-month breeder mice both developed ovarian inclusion cysts similar to serous cystadenomas. The majority of cysts appeared to be dilated rete ovarii tubules, but high ovulation number resulted in more cortical inclusion cysts. We hypothesized that comparison of inclusion cyst pathology in animals of the same age, but with differences in total lifetime ovulation number, might allow us to determine distinguishing characteristics of the two types of cyst.
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