New and recurrent STAT1 mutations in seven Chinese patients with chronic mucocutaneous candidiasis

New and recurrent STAT1 mutations in seven Chinese patients with chronic mucocutaneous candidiasis
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7 名中国慢性皮肤粘膜念珠菌病患者的新发和复发 STAT1 突变

DOI:
10.1111/ijd.13427
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发表时间:
2017-02
影响因子:
3.6
通讯作者:
Frank L. van de Veerdonk
Frank L. van de Veerdonk
中科院分区:
医学4区
文献类型:
--
作者:
Xiaowen Wang;Ruijun Zhang;Weiwei Wu;Aiping Wang;Zhe Wan;Ruoyu Li;Frank L. van de Veerdonk

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甚至在奥美拉唑作为人用药物上市之前就存在瘤病。许多药物正在被添加到药物清单中,导致皮肤的阴险色素沉着。应该祝贺蔡美儿等人采取了详细的历史,以确定可能的罪魁祸首在他们的案件。然而,除非在色素沉着区域证明药物,如第一例奥美拉唑诱导色素沉着的病例报告,否则可以认为色素沉着不一定由药物引起。总体而言,怀疑奥美拉唑是这些病例中色素沉着的原因似乎是合理的。
matosis existed even before omeprazole was marketed as a drug for human use. Many drugs are being added to the list of drugs causing insidious pigmentation of the skin. Chua et al. should be congratulated for taking a detailed history to identify the probable culprit in their cases. However, unless the drug is demonstrated in the pigmented areas, as in the first case report of omeprazole-induced pigmentation, it can be argued that the pigmentation is not necessarily caused by the drug. Overall, it appears reasonable to suspect omeprazole as the cause of pigmentation in these cases.
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