Fast high-resolution T1 mapping using inversion-recovery Look-Locker echo-planar imaging at steady state: optimization for accuracy and reliability.
Fast high-resolution T1 mapping using inversion-recovery Look-Locker echo-planar imaging at steady state: optimization for accuracy and reliability.
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DOI：
10.1002/mrm.21836
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发表时间：
2009-04
影响因子：
3.3
通讯作者：
Yang, Yihong
中科院分区：
文献类型：
--
作者：
Shin, Wanyong;Gu, Hong;Yang, Yihong
关键词：
提出了一种利用稳态反演恢复Look-Locker回波平面成像（IR LL-EPI SS）的快速T1测量序列。序列中不需要完全磁化恢复的延迟时间，从而大大节省了高分辨率T1映射的采集时间。对IR LL-EPI SS序列的成像参数进行了优化，以最大限度地减少激发脉冲缺陷带来的偏差，并最大限度地提高T1测量的准确性和可靠性，这对其应用至关重要。与传统的反演反演Look-Locker回波平面成像（IR LL-EPI）序列相比，IR LL-EPI SS方法保持了相似的精度和可靠性，同时节省了20%的采集时间。优化后的IR LL-EPI SS在大约4分钟内提供了1×1×4 mm3分辨率和全脑覆盖（28片）的定量T1制图。
A fast T1 measurement sequence using inversion recovery Look-Locker echo-planar imaging at steady state (IR LL-EPI SS) is presented. Delay time for a full magnetization recovery is not required in the sequence, saving acquisition time significantly for high-resolution T1 mapping. Imaging parameters of the IR LL-EPI SS sequence were optimized to minimize the bias from the excitation pulses imperfection and to maximize the accuracy and reliability of T1 measurements, which are critical for its applications. Compared with the conventional inversion recovery Look-Locker echo-planar imaging (IR LL-EPI) sequence, IR LL-EPI SS method preserves similar accuracy and reliability, while saving 20% in acquisition time. Optimized IR LL-EPI SS provided quantitative T1 mapping with 1×1×4 mm3 resolution and whole brain coverage (28 slices) in approximately 4 minutes.
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