Comparison of drug-induced sleep endoscopy and upper airway computed tomography in obstructive sleep apnea patients
Comparison of drug-induced sleep endoscopy and upper airway computed tomography in obstructive sleep apnea patients
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阻塞性睡眠呼吸暂停患者药物诱导睡眠内窥镜检查与上气道计算机断层扫描的比较
DOI：
10.1007/s00405-014-3051-1
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发表时间：
2014-04
影响因子：
2.6
通讯作者：
Kang Dan
中科院分区：
文献类型：
--
作者：
Zhang Peng;Ye Jingying;Pan Chuxiong;Xian Junfang;Sun Nian;Li Jingjing;Zhang Yuhuan;Kang Dan
本研究的目的是评估阻塞性睡眠呼吸暂停(OSA)患者药物诱导睡眠内窥镜(DISE)检查结果与上呼吸道CT(UACT)检查结果之间的关系。这项研究是一项非随机的前瞻性临床试验。我们使用DISE根据投票分类来识别障碍模式。62例受试者(均为男性)均表现为口膜相关梗阻，口咽外侧梗阻47例(75.8%)，舌根相关梗阻45例(72.6%)，会厌梗阻6例(9.7%)。以下UACT测量在有和无口咽侧方阻塞的受试者之间有显著差异(P<；P<；)：气道长度、喉咽长度、下颌平面到舌骨的距离、舌后气道的最小侧径、腭后前后径/侧径和舌后前后径/侧径。UACT测量结果在有无舌根或会厌梗阻的受试者之间没有显著差异。这些结果表明，在OSA患者中，使用这些UACT测量可以识别与口咽侧壁相关的阻塞。因此，在唤醒时执行的UACT可以部分取代既耗时又昂贵的DISE。
The purpose of the present study was to evaluate the associations between the findings of drug-induced sleep endoscopy (DISE) and upper airway computed tomography (UACT) in obstructive sleep apnea (OSA) patients. This study was a non-randomized, prospective, clinical trial. We used DISE to identify the obstruction pattern according to VOTE classification. All 62 study subjects (all men) showed velum-related obstruction; 47 (75.8 %) had lateral oropharyngeal obstruction, 45 (72.6 %) had tongue-base-related obstruction, and 6 (9.7 %) had epiglottal obstruction. The following UACT measurements significantly differed between subjects with and without lateral oropharyngeal obstruction (P< 0.05): airway length, laryngopharynx length, mandibular plane to hyoid distance, minimum lateral dimension of the retroglossal airway, retropalatal anteroposterior/lateral dimension, and retroglossal anteroposterior/lateral dimension. None of the UACT measurements significantly differed between subjects with and without tongue-base-related or epiglottal obstruction. These results indicate that in OSA patients, obstruction related to the lateral oropharyngeal walls can be identified using these UACT measurements. Thus, UACT, which is performed during wakefulness, can partially replace DISE, which is both time consuming and costly.
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影响因子：
2.6
作者：
Soares, Danny;Sinawe, Hadeer;Folbe, Adam J.;Yoo, George;Badr, Safwan;Rowley, James A.;Lin, Ho-Sheng
通讯作者：
Lin, Ho-Sheng
影响因子：
2.6
作者：
George, Jonathan R.;Chung, Sooyoun;Nielsen, Ib;Goldberg, Andrew N.;Miller, Arthur;Kezirian, Eric J.
通讯作者：
Kezirian, Eric J.
影响因子：
1.9
作者：
Abramson, Zachary;Susarla, Srinivas;Kaban, Leonard
通讯作者：
Kaban, Leonard
影响因子：
2.6
作者：
Koutsourelakis, Ioannis;Safiruddin, Faiza;de Vries, Nico
通讯作者：
de Vries, Nico
DOI：
10.1002/14651858.cd001004
发表时间：
1998-01
期刊：
The Cochrane database of systematic reviews
影响因子：
--
作者：
S. Sundaram;S. Bridgman;J. Lim;T. Lasserson
通讯作者：
S. Sundaram;S. Bridgman;J. Lim;T. Lasserson