Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis.
Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis.
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DOI：
10.1038/s41598-017-05024-6
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发表时间：
2017-07-06
影响因子：
4.6
通讯作者：
Hsu CM
中科院分区：
文献类型：
--
作者：
Tsai MS;Yang MY;Chang GH;Tsai YT;Lin MH;Hsu CM
内侧化喉成形术是单侧声带麻痹的标准手术治疗方法。本研究提出了一种改良的方法，其中甲状软骨移植物植入内侧化喉成形术。22名接受这种方法的患者被纳入研究。术后随访6 ~ 74个月，平均21.4个月，声门闭合不全和发声能力明显改善。声学分析显示，最大发声时间（从3.51秒到7.89秒，p < 0.001）、F0（从221.7赫兹到171.0赫兹，p = 0.025）和抖动（从7.68到3.19，p < 0.001）均有显著改善。感知评估显示，声音分级（从2.59到1.41，p < 0.001）、粗糙度（从1.82到1.23，p = 0.004）和声音呼吸（从2.55到1.23，p < 0.001）显著降低。没有患者表现出严重的伤口感染、组织排斥反应或其他外科手术引起的并发症。总之，自体甲状软骨移植在内侧化喉成形术中使声带内侧化，使声门间隙最小化，并改善声带麻痹患者的声音。该方法的特点是简单、安全和可接受的结果。
Medialization laryngoplasty is the standard surgical treatment for unilateral vocal fold paralysis. This study presents a modified approach in which a thyroid cartilage graft is implanted in medialization laryngoplasty. 22 patients who underwent this approach were included in the study. The results revealed that glottal incompetence and vocal performance were markedly improved following surgery, and the follow-up period ranged from 6 to 74 months (mean, 21.4 months). Acoustic analysis revealed significant improvements in the maximum phonation time (from 3.51 to 7.89 seconds, p < 0.001), F0 (from 221.7 to 171.0 Hertz, p = 0.025), and jitter (from 7.68 to 3.19, p < 0.001). Perceptual assessment revealed a significant decrease in voice grading (from 2.59 to 1.41, p < 0.001), roughness (from 1.82 to 1.23, p = 0.004), and voice breathiness (from 2.55 to 1.23, p < 0.001). None of the patients exhibited severe wound infection, tissue rejection, or other complications attributed to the surgical procedure. In conclusion, autologous thyroid cartilage implantation in medialization laryngoplasty medializes the vocal cord, minimizes the glottal gap, and improves the voice of patients with vocal fold paralysis. This procedure is characterized by simplicity, safety, and acceptable results.
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影响因子：
1.4
作者：
Isshiki, N
通讯作者：
Isshiki, N
影响因子：
3
作者：
Mesallam, Tamer A.;Khalil, Yasser A.;Farahat, Mohamad
通讯作者：
Farahat, Mohamad
影响因子：
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作者：
Fang, Tuan-Jen;Li, Hsueh-Yu;Chuang, Hsiu-Feng
通讯作者：
Chuang, Hsiu-Feng
影响因子：
2.2
作者：
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通讯作者：
Carding, Paul N.
影响因子：
2.6
作者：
KOUFMAN, JA;WALKER, FO;JOHARJI, GM
通讯作者：
JOHARJI, GM