Three-Dimensional Volumetric Changes After Socket Augmentation with Deproteinized Bovine Bone and Collagen Matrix.
Three-Dimensional Volumetric Changes After Socket Augmentation with Deproteinized Bovine Bone and Collagen Matrix.
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DOI：
10.11607/jomi.7961
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Marchesan J
中科院分区：
文献类型：
--
作者：
Morelli T;Zhang S;Monaghan E;Moss KL;Lopez B;Marchesan J
牙槽窝增大降低了牙槽嵴吸收的幅度，但文献在量化软组织重塑方面有限。本研究的目的是确定用异种胶原基质结合骨移植治疗牙槽窝扩大后硬组织和软组织颊面的体积和线性尺寸变化。二十四名需要拔牙的人参加了这项调查。每个参与者被随机分配到两组中的一组：1）脱蛋白牛骨+胶原蛋白塞，或2）脱蛋白牛骨+异种胶原基质。在拔牙前和拔牙后第 6 个月进行锥形束计算机断层扫描 (CBCT) 扫描。在基线、拔牙后第 3 个月和第 6 个月拍摄口腔内扫描图像。通过非接触式逆向工程软件进行硬组织和软组织分析，以比较线性牙槽嵴重塑和体积变化。两组均显示出骨骼和软组织重塑。对于硬组织重塑，胶原栓和胶原基质组之间没有显着差异。对于软组织重塑，与胶原栓组相比，胶原基质组显示软组织损失减少。体积分析表明，6 个月期间，胶原基质组的平均颊部软组织体积损失为 68.6mm3，而胶原栓组的平均颊软组织体积损失为 87.6mm3 (p=0.009)。这项临床研究提供了使用总组织体积来比较牙槽窝扩大后软组织和硬组织重塑的早期证据。这项研究的结果表明，使用异种胶原蛋白基质减少了拔牙后颊部软组织的损失，但还需要进一步的研究来评估拔牙后软组织增强的临床意义。
Socket augmentation decrease the magnitude of alveolar ridge resorption, but the literature is limited in respect of quantifying soft tissue remodeling. The aim of this study was to determine the volumetric and linear dimensional changes at the buccal surface for both hard and soft tissues after socket augmentation treated with a xenogeneic collagen matrix in combination with bone grafting. Twenty-four individuals indicated for tooth extraction were enrolled in this investigation. Each participant was randomly assigned to one of two groups: 1) deproteinized bovine bone+ collagen plug, or 2) deproteinized bovine bone + xenogeneic collagen matrix. A cone beam computed tomography (CBCT) scan was taken prior to extraction and at month-6 post-extraction. Intra-oral scanning images were taken at baseline, month-3, and month-6 post extraction. Hard and soft tissue analyses were performed to compare linear ridge remodeling and volumetric changes by a non-contact reverse engineering software. Both groups showed bone and soft tissue remodeling. For hard tissue remodeling there was no significant difference between collagen plug and collagen matrix groups. For soft tissue remodeling the collagen matrix group showed a reduced soft tissue loss compared to the collagen plug group. The volumetric analysis demonstrated that the average buccal soft tissue volume loss for the collagen matrix group was 68.6mm3 compared to 87.6mm3 found in the collagen plug group (p=0.009) over a 6-month period. This clinical investigation provides early evidence of using the total tissue volume to compare soft and hard tissue remodeling after socket augmentation. The results of this study demonstrated that the use of a xenogeneic collagen matrix reduced the buccal soft tissue loss after tooth extraction, but additional studies are necessary to evaluate the clinical significance of soft tissue augmentation after tooth extraction.
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影响因子：
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作者：
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