Predictors of quality of life in breast cancer patients under chemotherapy.
Predictors of quality of life in breast cancer patients under chemotherapy.
复制标题
化疗期间乳腺癌患者生活质量的预测因素。
DOI：
--
复制
发表时间：
2008
影响因子：
1
通讯作者：
M. Pourhoseingholi
中科院分区：
文献类型：
--
作者：
A. Safaee;B. Moghimi;B. Zeighami;Hamidreza Tabatabaee;M. Pourhoseingholi
背景
今天，生活质量研究在医疗保健特别是慢性疾病中发挥着重要作用。乳腺癌在妇女恶性肿瘤中居第三位。这种癌症的存活率很高然而，乳腺癌有几个影响患者生活的并发症。
旨在
本研究旨在评估接受化疗的乳腺癌患者的生活质量。
环境与设计
对2006年1月至2月期间在伊朗南部设拉子市Namazi医院化疗病房住院治疗的119名乳腺癌患者进行了一项横断面研究。
材料和方法
使用QLQ-C30问卷评估这些患者的生活质量。
统计分析
我们使用单变量方法。进行多元回归分析，以确定生活质量的预测因素。
结果
患者的平均年龄为48.27 ± 11.42岁，生活质量总分为64.92 ± 24.28。除食欲减退（P>0.05）和腹泻（P=0.752）外，其他症状量表与生活质量呈负相关。回归分析结果显示，只有肿瘤分级、职业状况、绝经状况、经济困难和呼吸困难对患者的生活质量有统计学意义。
结论
总之，这项研究表明，临床和社会人口因素与乳腺癌患者的生活质量之间的关系的强度。对诊断为乳腺癌的妇女提供心理和经济支持可能会提高生活质量。
BACKGROUND
Today, the quality of life studies has an important role in health care especially in chronic diseases. Breast cancer has third order among women's malignancies. Now, survival rate for this cancer is long. However breast cancer has several complications that affected the patient's life.
AIMS
The aim of this study was to assess the quality of life in Breast cancer patients under chemotherapy.
SETTING AND DESIGN
A cross-sectional study conducted on 119 breast cancer patients that were admitted and treated in chemotherapy ward of Namazi hospital in Shiraz city, south of Iran, between Jan and Feb 2006.
MATERIALS AND METHODS
The QLQ-C30 questionnaire was used to assess quality of life in these patients.
STATISTICAL ANALYSIS
We used univariate methods. A multiple regression analysis was performed to identify predictors of quality of life.
RESULTS
Mean age of patients was 48.27+/-11.42 with quality of life total score 64.92+/-24.28. All symptoms scales had reverse association with quality of life except appetite loss (P>0.05) and diarrhea (P=0.752). The results of the regression analyses showed that only grade of tumor, occupational status, menopausal status, financial difficulties and dyspnea were statistically significant in predicting patients' quality of life.
CONCLUSION
In conclusion, this study demonstrates the strength of the relationship between clinical and sociodemographical factors and breast cancer patients' quality of life. Psychological and financial support for women experiencing breast cancer diagnosis may improve quality of life.
影响因子：
10.3
作者：
Ganz, PA;Kwan, L;Belin, TR
通讯作者：
Belin, TR