Trends in personal and family member opioid prescriptions prior to a diagnosis of an opioid-related problem among adolescents and young adults.
Trends in personal and family member opioid prescriptions prior to a diagnosis of an opioid-related problem among adolescents and young adults.
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DOI：
10.1080/08897077.2021.1901175
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发表时间：
2021
期刊：
影响因子：
3.5
通讯作者：
Leslie, Douglas L.
中科院分区：
文献类型：
--
作者：
Cohrs, Austin C.;Pacula, Rosalie Liccardo;Dick, Andrew W.;Stein, Bradley D.;Druss, Benjamin G.;Leslie, Douglas L.
减少阿片类药物滥用风险的努力往往侧重于减少不必要的阿片类药物处方或减少处方剂量；然而，并不是所有的滥用都发生在有个人处方的个人身上。本研究调查了有阿片类药物相关问题（ORP）的青少年和年轻人（AYAs）的比例趋势，这些青少年和年轻人在ORP诊断之前也有个人阿片类药物处方药索赔或有家庭成员有阿片类药物处方药索赔。回顾性队列设计用于分析纵向索赔数据。我们确定了在2006年至2014年间新诊断为ORP的12至25岁的个体。检查ORP诊断前1年内个人或家庭阿片类处方药索赔随时间的趋势。我们发现53560例AYAs有ORP诊断。在整个研究期间，40%诊断为ORP的AYAs在诊断前一年有个人阿片类药物处方，48%的家庭成员在前一年有阿片类药物处方。家庭处方占比保持不变，个人处方占比从2006年的77.1%下降到2014年的27.3%。随着时间的推移，有ORP的AYAs数量增加，但在诊断前有个人阿片类药物处方索赔的比例随着时间的推移而下降。这表明，尽管给家庭成员开处方可能仍然是一个途径，但提供者正在更加关注直接给AYAs开阿片类药物。
Efforts to reduce the risk of opioid misuse are often focused on reducing unnecessary prescriptions for opioid medications or reducing the dose prescribed; however, not all misuse occurs in individuals with a personal prescription. This study examined trends in the proportion of adolescents and young adults (AYAs) who had an opioid-related problem (ORP) and who also had a personal opioid prescription drug claim or had a family member with an opioid prescription drug claim prior to the ORP diagnosis. A retrospective cohort design was used to analyze longitudinal claims data. We identified individuals aged 12 to 25 years who had a newly diagnosed ORP in the years 2006 to 2014. Trends over time in personal or family opioid prescription drug claims within 1 year prior to ORP diagnosis were examined. We identified 53,560 AYAs with an ORP diagnosis. Over the entire study period, 40% of AYAs with an ORP diagnosis had a personal opioid prescription in the year prior to diagnosis, and 48% had a family member with an opioid prescription in the prior year. While the proportion of AYAs with a family prescription remained constant, the proportion with a personal prescription fell from 77.1% in 2006 to 27.3% in 2014. The number of AYAs with an ORP increased over time, yet the proportion with a personal opioid prescription claim prior to their diagnosis decreased over time. This suggests that providers are paying greater attention to prescribing opioids to AYAs directly, although prescriptions to family members may still remain a point of access.
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