Omega-3/6 Fatty Acids and Learning in Children and Young People: A Review of Randomised Controlled Trials Published in the Last 5 Years
Omega-3/6 Fatty Acids and Learning in Children and Young People: A Review of Randomised Controlled Trials Published in the Last 5 Years
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Omega-3/6 脂肪酸与儿童和青少年的学习：过去 5 年发表的随机对照试验综述
DOI：
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
D. E
中科院分区：
文献类型：
--
作者：
Kirby A;D. E
帮助孩子学习和集中注意力是教育教学法的核心部分。鉴于人类大脑中约有60%是脂肪，本综述旨在评估omega-3/6脂肪酸在课堂学习方面的作用。这在现代尤其重要，因为儿童的脂肪酸谱发生了变化，ω-6与ω-3的比例增加。使用国家生物技术信息中心PubMed数据库，检索了2012年至2017年期间发表的所有符合规定纳入标准的研究。共有29项随机对照试验（RCT）使用Omega 3/6脂肪酸作为干预措施。22项研究（n= 3，336）显示了总体益处，从血液脂肪酸水平的改善到睡眠的改善。8项试验（n=768）招募了基线时患有ADHD的儿童和年轻人，报告了ADHD症状的具体改善。六项研究（n=1092）表明，ω 3/6脂肪酸可以支持学习（提高阅读能力，拼写，行为，注意力和减少多动症和侵略性）。最强的好处是那些：1）多动症或共病学习条件，2）次优欧米茄-3状态或3）谁在基线表现不佳。关注弱势群体的RCT，如照顾儿童（LAC）和那些有特殊学习困难的人，如阅读障碍和计算障碍，他们也可能从omega-3/6脂肪酸中受益，值得进一步研究。
Helping children to learn and focus is a central part of educational pedagogy. Given that the human brain is around 60 per cent fat the present review sets out to evaluate the role of omega-3/6 fatty acids in relation to aspects of classroom learning. This is particularly relevant in modern day given that there has been a shift in children’s fatty acids profiles, with movement towards an increased ratio of omega-6 to 3. Using the National Centre for Biotechnology Information PubMed database, a search was made for all studies published between 2012 and 2017 that met defined inclusion criteria. A total of 29 Randomised Controlled Trials (RCT) were identified which used Omega 3/6 fatty acids as interventions. Twenty-two studies (n=3,336) showed overall benefits, ranging from improvements in blood fatty acid levels to improved sleep. Eight trials (n=768) recruiting children and young people with ADHD at baseline reported specific improvements in ADHD symptoms. Six studies (n=1092) showed that omega 3/6 fatty acids can support learning (improved reading ability, spelling, behaviour, attention and reduced hyperactivity and aggression). Strongest benefits are seen amongst those with: 1) ADHD or comorbid learning conditions, 2) suboptimal omega-3 status or 3) who underperform at baseline. RCTs focusing on vulnerable groups such as Looked After Children (LAC) and those with specific learning difficulties such as dyslexia and dyscalculia who could also potentially benefit from omega-3/6 fatty acids warrant further investigation.
影响因子：
7.1
作者：
Baym, Carol L.;Khan, Naiman A.;Cohen, Neal J.
通讯作者：
Cohen, Neal J.
DOI：
10.1016/j.jaac.2014.01.018
发表时间：
2014-06
影响因子：
13.3
作者：
Bent, Stephen;Hendren, Robert L.;Zandi, Tara;Law, Kiely;Choi, Jae-Eun;Widjaja, Felicia;Kalb, Luther;Nestle, Jay;Law, Paul
通讯作者：
Law, Paul