A heated humidifier reduces upper airway dryness during continuous positive airway pressure therapy.
A heated humidifier reduces upper airway dryness during continuous positive airway pressure therapy.
复制标题
加热加湿器可减少持续气道正压治疗期间上呼吸道的干燥。
DOI：
10.1016/s0954-6111(99)90072-0
复制
发表时间：
1999
影响因子：
4.3
通讯作者：
Joachim H. Ficker
中科院分区：
文献类型：
--
作者：
G. Wiest;G. Lehnert;W. M. Bruck;Marco Meyer;Eckhart G. Hahn;Joachim H. Ficker
上呼吸道干燥是阻塞性睡眠呼吸暂停 (OSA) 经鼻持续正压通气 (nCPAP) 治疗的常见副作用。在这种情况下，常采用加热加湿的方法。或者，经常使用油性滴鼻剂来缓解干燥。本研究旨在研究加热加湿器与油性滴鼻剂相比的功效。 24 名主诉严重 nCPAP 相关上呼吸道干燥的 OSA 患者被随机接受为期 6 周的治疗，治疗包括加热湿化（HC 100®，Fischer & Paykel, Inc.，奥克兰，新西兰）或油性滴鼻剂（Colda-Stop®，Desitin, Inc.，德国）。患者完成了关于上气道干燥的程度和频率、nCPAP 的依从性、终止 nCPAP 的意愿以及 nCPAP 治疗期间的舒适度的调查问卷。所有 12 名接受加热湿化治疗的患者上呼吸道干燥的程度和频率均得到改善，并且在使用 nCPAP 装置时报告舒适度更高。加热湿化组中所有因上呼吸道干燥而打算终止 nCPAP 治疗的患者均在加湿的基础上继续使用 nCPAP。相比之下，油性滴鼻剂组的 12 名患者中，只有 5 名患者 (42%) 报告上呼吸道干燥程度得到改善 (P=0·003)，只有 3 名患者 (25%) 报告上呼吸道干燥频率有所改善 (P<0·001)，只有 5 名患者 (42%) 报告使用油性滴鼻剂使用 nCPAP 装置时更舒适 (P<0·001)。在使用油性滴鼻剂的组中，三名打算终止 nCPAP 治疗的患者均未坚持使用 nCPAP。在减少 nCPAP 期间上呼吸道干燥症状方面，加热加湿非常有效，并且优于油性滴鼻剂。
Upper airway dryness is a frequent side-effect of nasal continuous positive airway pressure (nCPAP) therapy in obstructive sleep apnoea (OSA). In this situation, heated humidification is often used. Alternatively, oily nose drops are frequently applied to relieve dryness. The present study aimed to investigate the efficacy of a heated humidifier in comparison with oily nose drops. Twenty-four OSA patients complaining of serious nCPAP-related upper airway dryness were randomized to 6 weeks of treatment either with heated humidification (HC 100®, Fischer & Paykel, Inc., Auckland, New Zealand) or oily nose drops (Colda-Stop®, Desitin, Inc., Germany). The patients completed questionnaires on the degree and frequency of upper airway dryness, compliance with nCPAP, intention to terminate nCPAP and comfort during the nCPAP therapy. All 12 patients treated with heated humidification improved in terms of the degree and frequency of upper airway dryness, and reported greater comfort when using the nCPAP device. All patients in the heated humidification group intending to terminate nCPAP therapy because of upper airway dryness persisted with nCPAP on addition of humidification. In contrast, only five out of 12 patients (42%) in the oily nose drops group reported their degree of upper airway dryness to be improved (P=0·003), only three patients (25%) reported an improvement in the frequency of upper airway dryness (P<0·001), and only five patients (42%) reported greater comfort when using the nCPAP device with oily nose drops (P<0·001). In the group using oily nose drops none of the three patients who intended to terminate nCPAP therapy persisted with nCPAP. Heated humidification is highly effective and superior to oily nose drops in reducing the symptoms of upper airway dryness during nCPAP.
影响因子：
158.5
作者：
YOUNG, T;PALTA, M;BADR, S
通讯作者：
BADR, S
影响因子：
9.6
作者：
Phillips,BA;Schmitt,FA;Berry,DT;Lamb,DG;Amin,M;Cook,YR
通讯作者：
Cook,YR