enoLOGOS: a versatile web tool for energy normalized sequence logos.
enoLOGOS: a versatile web tool for energy normalized sequence logos.
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Enologos:用于能量归一化序列徽标的多功能网络工具。
DOI:
10.1093/nar/gki439
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发表时间:
2005-07-01
影响因子:
14.9
通讯作者:
Benos, PV
中科院分区:
文献类型:
--
作者:
Workman, CT;Yin, YT;Corcoran, DL;Ideker, T;Stormo, GD;Benos, PV
enoLOGOS is a web-based tool that generates sequence logos from various input sources. Sequence logos have become a popular way to graphically represent DNA and amino acid sequence patterns from a set of aligned sequences. Each position of the alignment is represented by a column of stacked symbols with its total height reflecting the information content in this position. Currently, the available web servers are able to create logo images from a set of aligned sequences, but none of them generates weighted sequence logos directly from energy measurements or other sources. With the advent of high-throughput technologies for estimating the contact energy of different DNA sequences, tools that can create logos directly from binding affinity data are useful to researchers. enoLOGOS generates sequence logos from a variety of input data, including energy measurements, probability matrices, alignment matrices, count matrices and aligned sequences. Furthermore, enoLOGOS can represent the mutual information of different positions of the consensus sequence, a unique feature of this tool. Another web interface for our software, C2H2-enoLOGOS, generates logos for the DNA-binding preferences of the C2H2 zinc-finger transcription factor family members. enoLOGOS and C2H2-enoLOGOS are accessible over the web at .
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影响因子:
5.6
作者:
SCHNEIDER, TD;STORMO, GD;EHRENFEUCHT, A
通讯作者:
EHRENFEUCHT, A
影响因子:
--
作者:
SHANNON, CE
通讯作者:
SHANNON, CE
影响因子:
5.8
作者:
Stormo, GD
通讯作者:
Stormo, GD
影响因子:
5.6
作者:
BERG, OG;VONHIPPEL, PH
通讯作者:
VONHIPPEL, PH
影响因子:
14.9
作者:
Man, TK;Stormo, GD
通讯作者:
Stormo, GD