Multifaceted Clinical Effects of Echinochrome.
Multifaceted Clinical Effects of Echinochrome.
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DOI:
10.3390/md19080412
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发表时间:
2021-07-26
期刊:
影响因子:
5.4
通讯作者:
Han J
中科院分区:
文献类型:
--
作者:
Kim HK;Vasileva EA;Mishchenko NP;Fedoreyev SA;Han J
The marine drug histochrome is a special natural antioxidant. The active substance of the drug is echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone), the most abundant quinonoid pigment in sea urchins. The medicine is clinically used in cardiology and ophthalmology based on the unique properties of Ech A, which simultaneously block various links of free radical reactions. In the last decade, numerous studies have demonstrated the effectiveness of histochrome in various disease models without adverse effects. Here, we review the data on the various clinical effects and modes of action of Ech A in ophthalmic, cardiovascular, cerebrovascular, inflammatory, metabolic, and malignant diseases.
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DOI:
10.1007/bf00950127
发表时间:
1985-07-01
期刊:
BULLETIN OF THE ACADEMY OF SCIENCES OF THE USSR DIVISION OF CHEMICAL SCIENCE
影响因子:
--
作者:
BOGUSLAVSKAYA, LV;KHRAPOVA, NG;MAKSIMOV, OB
通讯作者:
MAKSIMOV, OB
影响因子:
2
作者:
Chiusa, M.;Timolati, F.;Zuppinger, C.
通讯作者:
Zuppinger, C.
影响因子:
4.7
作者:
Fahmy, Sohair R.;Zaki, Nashwah Ismail;Hassanein, Sarah S.
通讯作者:
Hassanein, Sarah S.
DOI:
10.1016/0010-406x(69)91347-4
发表时间:
1969-01-01
期刊:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY
影响因子:
--
作者:
ANDERSON, HA;MATHIESO.JW;THOMSON, RH
通讯作者:
THOMSON, RH
影响因子:
0.7
作者:
Afanas'ev, SA;Lasukova, TV;Chernyavskii, AM
通讯作者:
Chernyavskii, AM