Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography.
Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography.
复制标题
通过提升光刻轻松制造微流体表面增强拉曼散射装置
DOI:
10.1098/rsos.172034
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发表时间:
2018-04
影响因子:
3.5
通讯作者:
Ma H
中科院分区:
文献类型:
--
作者:
Wu Y;Jiang Y;Zheng X;Jia S;Zhu Z;Ren B;Ma H
We describe a facile and low-cost approach for a flexibly integrated surface-enhanced Raman scattering (SERS) substrate in microfluidic chips. Briefly, a SERS substrate was fabricated by the electrostatic assembling of gold nanoparticles, and shaped into designed patterns by subsequent lift-up soft lithography. The SERS micro-pattern could be further integrated within microfluidic channels conveniently. The resulting microfluidic SERS chip allowed ultrasensitive in situ SERS monitoring from the transparent glass window. With its advantages in simplicity, functionality and cost-effectiveness, this method could be readily expanded into optical microfluidic fabrication for biochemical applications.
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