Body energy homeostasis.

Body energy homeostasis.
复制标题

DOI:
10.1016/j.appet.2008.06.009
复制
发表时间:
2008-11
期刊:
影响因子:
5.4
通讯作者:
Powley, Terry L.
Powley, Terry L.
中科院分区:
医学2区
文献类型:
--
作者:
Keesey, Richard E.;Powley, Terry L.

文献摘要

参考文献

被引文献

相似文献

从克劳德·伯纳德和沃尔特·坎农的稳态角度回顾了身体能量调节的证据。考虑食物摄入和能量消耗在维持和防御能量平衡中的互补作用。特别关注能量消耗调整在此过程中发挥的作用以及最近确定其代谢基础的研究。接下来是考虑许多新识别的身体能量状态信号以及它们用来通知中央调节系统的路径和反馈回路。最后,描述和讨论了身体能量调节水平的各种自然发生的和实验引起的变化。结论是,尽管早期的研究人员没有明确认为能量是内部环境的调节特征,但最近的研究为判断身体能量的调节是另一个稳态过程提供了坚实的基础。
Evidence for the regulation of body energy is reviewed from the homeostatic perspective of Claude Bernard and Walter Cannon. Considered are the complementary roles of food intake and energy expenditure in the maintenance and defense of energy balance. Particular attention is paid to the roles adjustments in energy expenditure play in this process and to recent investigations identifying their metabolic underpinnings. This is followed by a consideration of the many newly-identified signals of body energy status and the pathways and feedback loops they utilize to inform the central regulating system. Finally, various naturally-occurring and experimentally-induced alterations in the regulated level of body energy are described and discussed. It is concluded that, though early investigators did not expressly consider energy a regulated feature of the milieu interieur, more recent research has provided a sound basis for judging the regulation of body energy to be another homeostatic process.
DOI: 10.1126/science.1124147
发表时间: 2006-05-12
期刊: SCIENCE
影响因子: 56.9
作者:
Cota, D;Proulx, K;Seeley, RJ
通讯作者: Seeley, RJ
DOI: 10.1038/sj.ijo.0801916
发表时间: 2001-12-01
影响因子: 4.9
作者:
Levin, BE
通讯作者: Levin, BE
DOI: 10.1152/ajpregu.1995.269.5.r1024
发表时间: 1995-11-01
影响因子: 2.8
作者:
LENNIE, TA;MCCARTHY, DO;KEESEY, RE
通讯作者: KEESEY, RE
DOI: 10.1139/z70-040
发表时间: 1970-01-01
期刊: CANADIAN JOURNAL OF ZOOLOGY - BACK YEAR PROJECT
影响因子: --
作者:
MROSOVSKY, N;FISHER, KC
通讯作者: FISHER, KC
DOI: 10.1152/ajpregu.00474.2002
发表时间: 2003-07-01
影响因子: 2.8
作者:
Rosenbaum, M;Vandenborne, K;Leibel, RL
通讯作者: Leibel, RL