Modeling of micturition characteristics based on prostatic stiffness modulation induced using hormones and adrenergic antagonists
Modeling of micturition characteristics based on prostatic stiffness modulation induced using hormones and adrenergic antagonists
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基于使用激素和肾上腺素能拮抗剂诱导的前列腺僵硬调节的排尿特征建模
DOI：
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发表时间：
1995
影响因子：
4.6
通讯作者：
Christos E. Constantinou
中科院分区：
文献类型：
--
作者：
O. Sadao;Christos E. Constantinou
作者提出了一种旨在评估前列腺硬度的生物传感器。使用激素诱导和肾上腺素能刺激来调节前列腺的硬度。结果表明，传感器足够准确，可以区分用作对照的软前列腺和因激素而变硬的前列腺。使用该系统检测肾上腺素能药物对前列腺僵硬产生的调节。构建了体现前列腺硬度、排尿频率和体积参数的电模型，证明前列腺硬度与排尿频率相关。<<ETX>>
The authors present a biosensor intended to evaluate prostatic stiffness. The stiffness of the prostate was modulated using hormonal induction and adrenergic stimulation. The results show that the sensor can be sufficiently accurate to discriminate between soft prostates used as controls and those stiffened with hormones. The modulation produced by an adrenergic agent on prostatic stiffness was detected using this system. An electrical model was constructed embodying the parameters of prostatic stiffness, micturition frequency, and volume, demonstrating that prostatic stiffness correlates with micturition frequency.<<ETX>>
DOI：
10.1159/000457575
发表时间：
1989
期刊：
Developmental pharmacology and therapeutics
影响因子：
--
作者：
Latifpour,J;Morita,T;O'Hollaren,B;Kondo,S;Weiss,RM
通讯作者：
Weiss,RM
年轻和年老雌性兔尿道中α肾上腺素能受体的药理学特征。
DOI：
--
发表时间：
1991
期刊：
The Journal of pharmacology and experimental therapeutics
影响因子：
--
作者：
Yoshida,M;Latifpour,J;Nishimoto,T;Weiss,RM
通讯作者：
Weiss,RM