Quantitative characterization of functional anatomical contributions to cognitive control under uncertainty.

Quantitative characterization of functional anatomical contributions to cognitive control under uncertainty.
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DOI:
10.1162/jocn_a_00554
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发表时间:
2014-07
影响因子:
3.2
通讯作者:
Hof PR
Hof PR
中科院分区:
医学3区
文献类型:
--
作者:
Fan J;Van Dam NT;Gu X;Liu X;Wang H;Tang CY;Hof PR

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虽然许多证据表明,在许多认知任务中,反应时间随着计算负荷的增加而增加,但很少有人尝试量化与认知控制需求增加相关的神经活动变化。在这项功能磁共振成像研究中,我们使用多数功能任务来量化计算负荷对大脑激活的影响,反映不确定条件下认知控制所实例化的心理过程。我们发现额顶扣带回(FPC)系统的激活以及反相关默认模式网络的失活随着信息熵的函数而参数变化,并通过信息理论模型进行估计。目前的研究结果表明,大脑动态网络(尤其是 FPC 系统)的活动变化与信息熵或不确定性相关,而不仅仅是冲突或其他通常提出的认知控制目标。
While much evidence indicates that reaction time increases as a function of computational load in many cognitive tasks, quantification of changes in neural activity related to increasing demand of cognitive control has rarely been attempted. In this functional magnetic resonance imaging study, we used a majority function task to quantify the effect of computational load on brain activation, reflecting the mental processes instantiated by cognitive control under conditions of uncertainty. We found that the activation of the fronto-parieto-cingulate (FPC) system as well as the deactivation of the anticorrelated default mode network varied parametrically as a function of information entropy, estimated with an information theoretic model. The current findings suggest that activity changes in the dynamic networks of the brain (especially the FPC system) track with information entropy or uncertainty, rather than only conflict or other commonly proposed targets of cognitive control.
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