Non-malignant disease mortality in meat workers: a model for studying the role of zoonotic transmissible agents in non-malignant chronic diseases in humans
Non-malignant disease mortality in meat workers: a model for studying the role of zoonotic transmissible agents in non-malignant chronic diseases in humans
复制标题
肉类工人的非恶性疾病死亡率：研究人畜共患传染媒介在人类非恶性慢性疾病中的作用的模型
DOI：
--
复制
发表时间：
2007
影响因子：
4.9
通讯作者：
N. Lewis
中科院分区：
文献类型：
--
作者：
Eric S. Johnson;Y. Zhou;M. Sall;M. E. Faramawi;N. Shah;A. Christopher;N. Lewis
背景：目前的研究工作主要集中在评估动物食品中存在的物质在人类慢性疾病病因学中的作用，而相对较少关注评估也存在的传染性物质的作用。肉类工人会接触食用动物及其产品中存在的多种传染性病原体。本研究调查了接触这些暴露的工人因非恶性疾病而死亡的情况。方法：1949 年至 1989 年间，对马里兰州巴尔的摩一个工会的 8520 名肉类工人进行了一项队列死亡率研究，这些工人在屠宰或加工动物的制造工厂工作，并且高度接触传染性病原体。将肉类工人的死亡率与同一工会 6081 名工人的对照组以及美国总人口进行比较。风险通过比例死亡率、标准化死亡率（SMR）和相对 SMR 来估计。结果：与对照组或美国普通人群相比，肉类工人因败血症、蛛网膜下腔出血、慢性肾炎、急性和亚急性心内膜炎、心脏功能性疾病而死亡的人数明显增多，并且因脑前、脑动脉狭窄而死亡的风险降低。结论：作者假设，食用动物及其产品中存在的人畜共患传染媒介可能是肉类工人以及可能接触这些媒介的一般人群中出现一些循环系统、神经系统和其他疾病病例的原因。
Background: Current research efforts have mainly concentrated on evaluating the role of substances present in animal food in the aetiology of chronic diseases in humans, with relatively little attention given to evaluating the role of transmissible agents that are also present. Meat workers are exposed to a variety of transmissible agents present in food animals and their products. This study investigates mortality from non-malignant diseases in workers with these exposures. Methods: A cohort mortality study was conducted between 1949 and 1989, of 8520 meat workers in a union in Baltimore, Maryland, who worked in manufacturing plants where animals were killed or processed, and who had high exposures to transmissible agents. Mortality in meat workers was compared with that in a control group of 6081 workers in the same union, and also with the US general population. Risk was estimated by proportional mortality and standardised mortality ratios (SMRs) and relative SMR. Results: A clear excess of mortality from septicaemia, subarachnoid haemorrhage, chronic nephritis, acute and subacute endocarditis, functional diseases of the heart, and decreased risk of mortality from pre-cerebral, cerebral artery stenosis were observed in meat workers when compared to the control group or to the US general population. Conclusions: The authors hypothesise that zoonotic transmissible agents present in food animals and their products may be responsible for the occurrence of some cases of circulatory, neurological and other diseases in meat workers, and possibly in the general population exposed to these agents.
超市肉类工人的非癌症死亡率。
影响因子：
3.2
作者：
Johnson,EricS;Zhou,Yi
通讯作者：
Zhou,Yi
影响因子：
158.5
作者：
WILLETT, WC;STAMPFER, MJ;SPEIZER, FE
通讯作者：
SPEIZER, FE
影响因子：
5.3
作者：
Alavanja, MCR;Field, RW;Lynch, CF
通讯作者：
Lynch, CF