Investigation of microfluidic co-flow effects on step emulsification: Wall contact angle and critical dimensions
Investigation of microfluidic co-flow effects on step emulsification: Wall contact angle and critical dimensions
复制标题
研究微流体协流对分步乳化的影响：壁接触角和临界尺寸
DOI：
10.1016/j.colsurfa.2019.123733
复制
发表时间：
2019-11
期刊：
影响因子：
--
通讯作者：
Ruan Xiaodong
中科院分区：
文献类型：
--
作者：
Lian Jiaoyuan;Zheng Suxia;Liu Cong;Xu Zhongbin;Ruan Xiaodong
我们提出了一种并流分步乳化策略，用于在线控制微滴的产生。本文通过数值模拟和实验研究了接触角、平台长度、通道距离和通道直径四个参数的影响。结果表明，壁面接触角对液滴的形成至关重要，并流可将其适用范围扩大到90° ~ 180 °。平台长度对液滴生成的影响被并流减小，并且液滴直径几乎与平台长度无关，其范围为0.7至1.5mm。此外，液滴直径随着通道距离和直径的增加而显著增加。结合这些结果与我们以前的研究，我们推导出一个显式的液滴直径预测方程。基于该方程预测的液滴直径与模拟和实验结果吻合较好。提出了一个与物理参数和尺寸参数有关的系数α，用于预测并流分步乳化过程的状态和模式。本研究结论不仅为分步乳化芯片的设计和改进提供了重要参考，而且为可调单分散微滴的生产提供了新的思路和科学依据。
We propose a co-flowing step emulsification strategy for the on-line control of micro-droplet generation. The effects of four parameters including wall contact angle, plateau length, channel distance and diameter are investigated numerically and experimentally in this study. The results indicate that the wall contact angle, whose applicable range can be expanded to 90°–180° by co-flow, is critical to droplet formation. The effect of the plateau length on droplet generation is reduced by the co-flow, and the droplet diameter is almost independent of the plateau length, which ranges from 0.7 to 1.5 mm. In addition, the droplet diameter increases significantly with increasing channel distance and diameter. Combining these results with those of our previous study, we derived an explicit equation for droplet diameter prediction. The predicted droplet diameter based on this equation has good agreement with the simulation and experimental results. Furthermore, we proposed a coefficientαas a function of physical and dimensional parameters to predict the regimes and modes in the co-flowing step emulsification process. The conclusion of this study not only provides an important reference for the design and improvement of step emulsification chips, but also offers a new idea and a scientific basis for tuneable monodisperse micro-droplet production.
登录
查看更多内容
DOI：
10.1016/j.ijmultiphaseflow.2016.10.008
发表时间：
2017-03
影响因子：
3.8
作者：
J. Ruiz-Rus;R. Bolaños-Jiménez;C. Gutiérrez-Montes;A. Sevilla;C. Martínez-Bazán
通讯作者：
J. Ruiz-Rus;R. Bolaños-Jiménez;C. Gutiérrez-Montes;A. Sevilla;C. Martínez-Bazán
DOI：
10.1103/physreve.87.013002
发表时间：
2013
期刊：
Physical review. E, Statistical, nonlinear, and soft matter physics
影响因子：
--
作者：
Yongping Chen;Liangyu Wu;Chengbin Zhang
通讯作者：
Yongping Chen;Liangyu Wu;Chengbin Zhang
影响因子：
5.8
作者：
Gallarate, M;Carlotti, ME;Bovo, S
通讯作者：
Bovo, S
DOI：
10.1016/j.ijmultiphaseflow.2012.11.003
发表时间：
2013-04
影响因子：
3.8
作者：
C. Gutiérrez-Montes;R. Bolaños-Jiménez;A. Sevilla;C. Martínez-Bazán
通讯作者：
C. Gutiérrez-Montes;R. Bolaños-Jiménez;A. Sevilla;C. Martínez-Bazán
影响因子：
3.9
作者：
Nabavi, Seyed Ali;Vladisavljevic, Goran T.;Manovic, Vasilije
通讯作者：
Manovic, Vasilije