Association between life space and risk of mortality in advanced age.

Association between life space and risk of mortality in advanced age.
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DOI:
10.1111/j.1532-5415.2010.03058.x
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发表时间:
2010-10
影响因子:
6.3
通讯作者:
Bennett DA
Bennett DA
中科院分区:
医学1区
文献类型:
--
作者:
Boyle PA;Buchman AS;Barnes LL;James BD;Bennett DA

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研究生活空间与社区老年人死亡风险之间的联系,生活空间是一种衡量功能状态的指标,描述了在日常运作期间在所覆盖的环境中的活动范围。两项正在进行的关于老龄化的前瞻性观察队列研究。芝加哥大都会地区。1,445非痴呆症社区老年人。生活空间是通过一系列问题来衡量的,这些问题旨在衡量参与者在从卧室到城外的整个环境中的活动程度。使用根据年龄、性别、种族和教育进行调整的比例风险模型来检验生活空间和死亡率之间的关联。在长达8年的随访中(平均4.1年),1445名参与者中有329人死亡(22.8%)。在根据年龄、性别、种族和教育调整的比例风险模型中,越狭窄的生活空间与更大的死亡风险相关(危险比=1.18,95%可信区间=1.09-1.27,P<.001),因此生活空间受限于其直接家庭环境(得分=3)的人死亡的可能性大约是那些生活空间包括外出旅行(得分=0)的人的1.6倍。在添加了几个潜在混杂因素的术语后,这种联系仍然存在,这些混杂因素包括体力活动、基于表现的身体功能、残疾、抑郁症状、社会网络、体重指数和慢性疾病的数量。在以社区为基础的老年人中,有限的生活空间与更大的死亡风险有关。
To examine the association between life space, a measure of functional status that describes the range of movement through the environment covered during daily functioning, and the risk of mortality in older community-based persons. Two ongoing, prospective observational cohort studies of aging. Greater metropolitan Chicago area. One thousand four hundred forty-five community-based older persons without dementia. Life space was measured at baseline using a series of questions designed to measure the extent of participants’ movement throughout their environment, ranging from the bedroom to out of town. The association between life space and mortality was examined using proportional hazards models adjusted for age, sex, race, and education. Over up to 8 years of follow-up (mean 4.1 years), 329 of 1,445 (22.8%) participants died. In a proportional hazards model adjusted for age, sex, race, and education, a more-constricted life space was associated with a greater risk of death (hazard ratio = 1.18, 95% confidence interval = 1.09–1.27, P < .001), such that people with life spaces constricted to their immediate home environment (score = 3) were approximately 1.6 times as likely to die as those whose life spaces included trips out of town (score = 0). This association persisted after the addition of terms for several potential confounders, including physical activity, performance-based physical function, disability, depressive symptoms, social networks, body mass index, and number of chronic medical conditions. Constricted life space is associated with greater risk of death in older community-based persons.
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