Cellular and acellular pertussis vaccines in adults.
Cellular and acellular pertussis vaccines in adults.
复制标题
成人细胞和非细胞百日咳疫苗。
DOI:
10.1086/515064
复制
发表时间:
1999
期刊:
影响因子:
--
通讯作者:
W. Keitel
中科院分区:
文献类型:
--
作者:
W. Keitel
Immunization against pertussis after childhood previously was considered unnecessary, because severe illness and complications rarely developed in older persons. The rising incidence of pertussis among older adolescents and adults and the transmission of infection from adults to infants suggest that booster immunization may be necessary to more effectively control pertussis in all age groups. Whole cell pertussis vaccines are regarded as unsuitable for routine use in adults because of reports of frequent moderate to severe reactogenicity at the injection site and occasional systemic reactions. The introduction of safe and effective acellular pertussis vaccines provides us with an opportunity to reconsider booster immunization of adolescents and adults. Several vaccines containing purified component(s) of Bordetella pertussis have been well tolerated and highly immunogenic when given to healthy adults. A clear understanding of the impact of pertussis in adolescents and adults will help to define the need for booster immunization after childhood.
DOI:
10.1093/clinids/22.1.59
发表时间:
1996
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
作者:
Halperin,SA;Langley,JM;Eastwood,BJ
通讯作者:
Eastwood,BJ
DOI:
--
发表时间:
1995
期刊:
Seminars in respiratory infections
影响因子:
--
作者:
Keitel,WA;Edwards,KM
通讯作者:
Edwards,KM
DOI:
10.1086/314869
发表时间:
1999
期刊:
The Journal of infectious diseases
影响因子:
--
作者:
Keitel,WA;Muenz,LR;Decker,MD;Englund,JA;Mink,CM;Blumberg,DA;Edwards,KM
通讯作者:
Edwards,KM