Chronic sleep deprivation and seasonality: implications for the obesity epidemic.

Chronic sleep deprivation and seasonality: implications for the obesity epidemic.
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DOI:
10.3275/7808
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发表时间:
2011-11
影响因子:
5.4
通讯作者:
de Jonge L
de Jonge L
中科院分区:
医学3区
文献类型:
--
作者:
Cizza G;Requena M;Galli G;de Jonge L

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在过去的100年里,睡眠时间逐渐减少,而肥胖在过去的30年里有所增加。一些研究报告了长期睡眠不足和长期体重增加之间的联系。睡眠不足导致的能量摄入增加被列为主要机制。长期睡眠剥夺对能量消耗的影响尚未得到充分研究。睡眠、体重、情绪和行为都是周期性变化的。然而,在我们的现代环境中,光线和环境温度的季节性变化减弱了。季节性,被定义为情绪和行为的周期性变化,是一种具有强烈遗传成分的稳定人格特征。我们假设,环境中季节性变化的衰减可能会产生负面影响,特别是对更容易受季节性影响的个体,如女性。季节性情感障碍是一种在女性中更为常见的疾病,其特征是冬季情绪低落、嗜睡、体重增加和对碳水化合物的渴望,这是季节性的一个极端例子。睡眠的一个假定功能是保存能量。冬眠,一种以能量消耗减少和觉醒状态变化为特征的现象,可能为了解睡眠中能量保存背后的机制提供有用的见解。本文的目标是:a)考虑由于睡眠不足导致的体重增加对能量消耗变化的贡献;B)回顾季节性、冬眠现象及其与睡眠、能量消耗和体重调节相关的神经内分泌机制。
Sleep duration has progressively fallen over the last 100 years while obesity has increased in the past 30 years. Several studies have reported an association between chronic sleep deprivation and long-term weight gain. Increased energy intake due to sleep loss has been listed as the main mechanism. The consequences of chronic sleep deprivation on energy expenditure have not been fully explored. Sleep, body weight, mood and behavior are subjected to circannual changes. However, in our modern environment seasonal changes in light and ambient temperature are attenuated. Seasonality, defined as cyclic changes in mood and behavior, is a stable personality trait with a strong genetic component. We hypothesize that the attenuation in seasonal changes in the environment may produce negative consequences, especially in individuals more predisposed to seasonality, such as women. Seasonal affective disorder, a condition more common in women and characterized by depressed mood, hypersomnia, weight gain, and carbohydrate craving during the winter, represents an extreme example of seasonality. One of the postulated functions of sleep is energy preservation. Hibernation, a phenomenon characterized by decreased energy expenditure and changes in the state of arousal, may offer useful insight into the mechanisms behind energy preservation during sleep. The goals of this article are to: a) consider the contribution of changes in energy expenditure to the weight gain due to sleep loss; b) review the phenomena of seasonality, hibernation, and their neuroendocrine mechanisms as they relate to sleep, energy expenditure, and body weight regulation.
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