Cognit activation: a mechanism enabling temporal integration in working memory.

Cognit activation: a mechanism enabling temporal integration in working memory.
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DOI:
10.1016/j.tics.2012.03.005
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发表时间:
2012-04
影响因子:
19.9
通讯作者:
Bressler, Steven L.
Bressler, Steven L.
中科院分区:
心理学1区
文献类型:
--
作者:
Fuster, Joaquin M.;Bressler, Steven L.

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工作记忆对于在目标导向行为、推理和语言中跨时间整合信息至关重要,但其神经基础尚不清楚。基于最近的研究,我们提出了一种机制,大脑可以保留工作记忆的前瞻性使用,从而在感知/行动周期的时间桥接。认知机制的本质是激活认知,认知由分布的、重叠的和相互作用的皮层网络组成,这些网络聚集在一起编码受试者的长期记忆。工作记忆分别依赖于后额叶皮层的知觉认知和执行认知之间的兴奋性折返。鉴于工作记忆在构建有目的的认知序列中的普遍作用,其机制对于行为、推理和语言的基础至关重要。
Working memory is critical to the integration of information across time in goal-directed behavior, reasoning and language, yet its neural substrate is unknown. Based on recent research, we propose a mechanism by which the brain can retain working memory for prospective use, thereby bridging time in the perception/action cycle. The essence of the mechanism is the activation of cognits, which consist of distributed, overlapping and interactive cortical networks that in the aggregate encode the long-term memory of the subject. Working memory depends on the excitatory reentry between perceptual and executive cognits of posterior and frontal cortices, respectively. Given the pervasive role of working memory in the structuring of purposeful cognitive sequences, its mechanism looms essential to the foundation of behavior, reasoning and language.
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