Biomedical and Antioxidant Potentialities in Chilli: Perspectives and Way Forward.
Biomedical and Antioxidant Potentialities in Chilli: Perspectives and Way Forward.
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辣椒中的生物医学和抗氧化潜力：观点和前进的道路。
DOI：
10.3390/molecules27196380
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发表时间：
2022-09-27
期刊：
影响因子：
4.6
通讯作者：
Yadav, Dharmendra K.
中科院分区：
文献类型：
--
作者：
Bal, Solanki;Sharangi, Amit Baran;Upadhyay, Tarun Kumar;Khan, Fahad;Pandey, Pratibha;Siddiqui, Samra;Saeed, Mohd;Lee, Hae-Jeung;Yadav, Dharmendra K.
关键词：
在世界范围内，自古以来和当今，传统医学因其生物多样性而闻名，这极大地促进了补充和替代药物的进步和发展。有多种香料、药草和树木以其药用而闻名。辣椒是一种蔬菜兼香料作物，富含天然生物活性化合物、类黄酮、辣椒素、植物化学物质、植物营养素和具有潜在健康益处的药理活性化合物。此类化合物通过协同作用和联合作用表现出其优于单独处理的功能。这些化合物和营养素的共同作用使它们能够有效对抗凝血、肥胖、糖尿病、炎症、癌症等可怕疾病和微生物疾病，同时还具有良好的抗氧化剂，具有清除自由基和氧气的能力。近年来，辣椒素尤其是辣椒素可以改善重要的病毒性疾病，例如 SARS-CoV-2。此外，辣椒素使辣椒能够作为局部缓解疼痛的药物，并且作为一种潜在的有效麻醉剂对人类有益。所涉及的此类植物化学物质不仅使它们变得有用且成为神奇/人造药物的更经济的替代品，而且可以被用作生产新物质的淫秽药物。 TRPV1 受体与辣椒素在缓解慢性疾病方面的作用也在这项研究中得到了证实。尽管如此，有关食用辣椒的医学研究仍然有限，需要通过动物研究来证实结果。在这个作品中，我们努力以一种易于理解的方式阐述辣椒的营养和生物医学观点，这可以精确地升级和丰富我们的制药工业，以实现人类福祉。
Worldwide, since ages and nowadays, traditional medicine is well known, owing to its biodiversity, which immensely contributed to the advancement and development of complementary and alternative medicines. There is a wide range of spices, herbs, and trees known for their medicinal uses. Chilli peppers, a vegetable cum spice crop, are bestowed with natural bioactive compounds, flavonoids, capsaicinoids, phytochemicals, phytonutrients, and pharmacologically active compounds with potential health benefits. Such compounds manifest their functionality over solo-treatment by operating in synergy and consortium. Co-action of these compounds and nutrients make them potentially effective against coagulation, obesity, diabetes, inflammation, dreadful diseases, such as cancer, and microbial diseases, alongside having good anti-oxidants with scavenging ability to free radicals and oxygen. In recent times, capsaicinoids especially capsaicin can ameliorate important viral diseases, such as SARS-CoV-2. In addition, capsaicin provides an ability to chilli peppers to ramify as topical agents in pain-relief and also benefitting man as a potential effective anesthetic agent. Such phytochemicals involved not only make them useful and a much economical substitute to wonder/artificial drugs but can be exploited as obscene drugs for the production of novel stuffs. The responsibility of the TRPV1 receptor in association with capsaicin in mitigating chronic diseases has also been justified in this study. Nonetheless, medicinal studies pertaining to consumption of chilli peppers are limited and demand confirmation of the findings from animal studies. In this artifact, an effort has been made to address in an accessible format the nutritional and biomedical perspectives of chilli pepper, which could precisely upgrade and enrich our pharmaceutical industries towards human well-being.
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影响因子：
8.8
作者：
Barbero, Gerardo F.;Ruiz, Aurora G.;Barroso, Carmelo G.
通讯作者：
Barroso, Carmelo G.
影响因子：
4.3
作者：
Akagi, A;Sano, N;Izumi, K
通讯作者：
Izumi, K
影响因子：
4.7
作者：
Amantini, C.;Mosca, M.;Santoni, G.
通讯作者：
Santoni, G.
影响因子：
2.9
作者：
Alberti, A.;Galasso, V.;Pichierri, F.
通讯作者：
Pichierri, F.
DOI：
10.22271/09746315.2019.v15.i3.1245
发表时间：
2019-01-01
期刊：
Journal of Crop and Weed
影响因子：
--
作者：
Bal, S.;Maity, T. K.;Majumder, A.
通讯作者：
Majumder, A.