Illicit use of pharmaceutical opioids among young polydrug users in Ohio.

Illicit use of pharmaceutical opioids among young polydrug users in Ohio.
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DOI:
10.1016/j.addbeh.2009.03.037
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发表时间:
2009-08
影响因子:
4.4
通讯作者:
Carlson, R. G.
Carlson, R. G.
中科院分区:
医学2区
文献类型:
--
作者:
Daniulaityte, R.;Falck, R. S.;Wang, J.;Carlson, R. G.

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这项研究在俄亥俄州哥伦布市进行,在2002-2003年采用受访者驱动抽样方法招募了有MDMA/摇头丸使用史的年轻人(n=402),确定了当前(过去30天)非法使用药物阿片类药物的预测因素。为了符合条件,参与者必须在18-30岁之间,没有参与药物滥用治疗,并且报告在过去6个月内至少使用过一次MDMA/摇头丸。约81%的人报告终生使用,31%以上的人报告目前非法使用阿片类药物。逻辑回归分析显示,非法使用药物镇静剂和药物兴奋剂是非法使用药物阿片类药物的最强预测因素。在抑郁症状程度较高且报告目前使用致幻剂和吸入剂的人群中,使用药物类阿片的风险也较大。我们的研究结果表明,药物阿片类药物的非医疗使用是多种药物使用做法的一部分,通常包括非法使用其他处方药。观察到的抑郁症状与非法使用阿片类药物之间的关系可能对预防规划具有重要意义,应在未来的研究中加以审查。
This study, conducted in Columbus, Ohio, identified the predictors of current (past 30 day) illicit use of pharmaceutical opioids among young individuals (n=402) with a history of MDMA/ecstasy use who were recruited in 2002–2003 using respondent-driven sampling. To be eligible, participants had to be 18–30 years old, not involved in a drug abuse treatment, and report MDMA/ecstasy use at least once in the past 6 months. About 81% reported lifetime, and more than 31% reported current illicit use of pharmaceutical opioids. Logistic regression analysis revealed that illicit use of pharmaceutical tranquilizers and pharmaceutical stimulants were the strongest predictors of illicit use of pharmaceutical opioids. Risk of pharmaceutical opioid use was also greater among those who had higher levels of depressive symptoms and reported current use of hallucinogens and inhalants. Our findings suggest that the non-medical use of pharmaceutical opioids is a part of polydrug use practices that often incorporate illicit use of other prescription drugs. The observed relationship between depressive symptoms and illicit use of pharmaceutical opioids may have important implications for prevention programming and should be examined in future research.
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