Patients' request for and emergency physicians' prescription of antimicrobial prophylaxis for anthrax during the 2001 bioterrorism-related outbreak.
Patients' request for and emergency physicians' prescription of antimicrobial prophylaxis for anthrax during the 2001 bioterrorism-related outbreak.
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DOI：
10.1186/1471-2458-5-2
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发表时间：
2005-01-05
影响因子：
4.5
通讯作者：
Lautenbach E
中科院分区：
文献类型：
--
作者：
M'ikanatha NM;Julian KG;Kunselman AR;Aber RC;Rankin JT;Lautenbach E
担心在生物恐怖主义事件期间接触生物制剂的个人不当使用抗生素是一个重要的公共卫生问题。然而，很少有记录的程度，自我认定的炭疽暴露风险的个人接近医生的抗菌预防在2001年生物恐怖主义袭击在美国。我们进行了一项随机选择的美国急诊医师学会宾夕法尼亚分会成员的电话调查，以评估2001年炭疽袭击期间患者对抗菌药物的要求和急诊医生的处方。97名医生完成了调查。64（66%）的受访者收到了炭疽预防的病人的要求，16（25%），这些医生处方抗生素，共23名患者。10名医生处方了环丙沙星，8名医生处方了强力霉素。在2001年的生物恐怖袭击中，我们调查的大多数急诊医生都遇到了要求炭疽预防的病人。公众的担忧可能会导致生物恐怖主义事件期间对抗生素预防的高需求。阐明公共卫生对疫情的反应与结果之间的关系将有助于减轻一线临床医生的负担，并指导在生物恐怖事件期间控制抗生素分配不当的战略。
Inappropriate use of antibiotics by individuals worried about biological agent exposures during bioterrorism events is an important public health concern. However, little is documented about the extent to which individuals with self-identified risk of anthrax exposure approached physicians for antimicrobial prophylaxis during the 2001 bioterrorism attacks in the United States. We conducted a telephone survey of randomly selected members of the Pennsylvania Chapter of the American College of Emergency Physicians to assess patients' request for and emergency physicians' prescription of antimicrobial agents during the 2001 anthrax attacks. Ninety-seven physicians completed the survey. Sixty-four (66%) respondents had received requests from patients for anthrax prophylaxis; 16 (25%) of these physicians prescribed antibiotics to a total of 23 patients. Ten physicians prescribed ciprofloxacin while 8 physicians prescribed doxycycline. During the 2001 bioterrorist attacks, the majority of the emergency physicians we surveyed encountered patients who requested anthrax prophylaxis. Public fears may lead to a high demand for antibiotic prophylaxis during bioterrorism events. Elucidation of the relationship between public health response to outbreaks and outcomes would yield insights to ease burden on frontline clinicians and guide strategies to control inappropriate antibiotic allocation during bioterrorist events.
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影响因子：
11.8
作者：
Mott, JA;Treadwell, TA;Butler, JC
通讯作者：
Butler, JC
DOI：
10.1089/153871303771861469
发表时间：
2003-01-01
期刊：
Biosecurity and bioterrorism : biodefense strategy, practice, and science
影响因子：
--
作者：
M'ikanatha, Nkuchia M;Lautenbach, Ebbing;Aber, Robert C
通讯作者：
Aber, Robert C
影响因子：
120.7
作者：
Silver, RC;Holman, EA;Gil-Rivas, V
通讯作者：
Gil-Rivas, V
DOI：
10.1331/154434503321831085
发表时间：
2003-05-01
期刊：
Journal of the American Pharmacists Association : JAPhA
影响因子：
--
作者：
Brinker, Allen;Pamer, Carol;Beitz, Julie
通讯作者：
Beitz, Julie
影响因子：
120.7
作者：
Inglesby, TV;Henderson, DA;Tonat, K
通讯作者：
Tonat, K