Multiple phytochrome-interacting bHLH transcription factors repress premature seedling photomorphogenesis in darkness.
Multiple phytochrome-interacting bHLH transcription factors repress premature seedling photomorphogenesis in darkness.
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DOI：
10.1016/j.cub.2008.10.058
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发表时间：
2008-12-09
期刊：
影响因子：
9.2
通讯作者：
Quail, Peter H.
中科院分区：
文献类型：
--
作者：
Leivar, Pablo;Monte, Elena;Oka, Yoshito;Liu, Tiffany;Carle, Christine;Castillon, Alicia;Huq, Enamul;Quail, Peter H.
陆生开花植物在陆地上成功定居的一个重要因素是一种发展策略的演变，称为skotomorphogenesis，即从埋藏的种子中萌发的幼苗在地下黑暗中向土壤表面蓬勃向上生长。在这里，我们提供的遗传证据表明，这种策略的机制的核心组成部分是集体镇压过早的光形态发生的发展在黑暗中生长的幼苗由几个成员的光敏色素（PHY）相互作用因子（PIF）的bHLH转录因子（PIF1，PIF3，PIF4和PIF5）的亚家族。相反，这里和其他地方提出的证据，共同表明，一个重要的组成部分的机制，光启动光形态建成后，第一次曝光的黑暗生长的幼苗照射涉及逆转这种镇压的迅速减少，这些PIF蛋白的丰度，通过降解诱导的光活化的phy分子与转录因子的直接相互作用。我们的结论是，bHLH转录因子PIF1，PIF3，PIF4和PIF5作为组成型阻遏物的光形态发生在黑暗中，行动是迅速废除后，这些PIFs的phy诱导的蛋白水解降解曝光，允许启动光形态发生。
An important contributing factor to the success of terrestrial flowering plants in colonizing the land was the evolution of a developmental strategy, termed skotomorphogenesis, whereby post-germinative seedlings emerging from buried seed grow vigorously upward in the subterranean darkness toward the soil surface. Here we provide genetic evidence that a central component of the mechanism underlying this strategy is the collective repression of premature photomorphogenic development in dark-grown seedlings by several members of the phytochrome (phy)-interacting factor (PIF) subfamily of bHLH transcription factors (PIF1, PIF3, PIF4 and PIF5). Conversely, evidence presented here and elsewhere, collectively indicates that a significant component of the mechanism by which light initiates photomorphogenesis upon first exposure of dark-grown seedlings to irradiation involves reversal of this repression by rapid reduction in the abundance of these PIF proteins, through degradation induced by direct interaction of the photoactivated phy molecule with the transcription factors. We conclude that bHLH transcription factors PIF1, PIF3, PIF4 and PIF5 act as constitutive repressors of photomorphogenesis in the dark, action that is rapidly abrogated upon light exposure by phy-induced proteolytic degradation of these PIFs, allowing the initiation of photomorphogenesis to occur.
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影响因子：
7.2
作者：
Alabadi, David;Gallego-Bartolome, Javier;Blazquez, Miguel A.
通讯作者：
Blazquez, Miguel A.
影响因子：
64.8
作者：
Nozue, Kazunari;Covington, Michael F.;Maloof, Julin N.
通讯作者：
Maloof, Julin N.
影响因子：
3.1
作者：
Magliano, TA;Casal, JJ
通讯作者：
Casal, JJ
影响因子：
11.6
作者：
Oh, E;Kim, J;Choi, G
通讯作者：
Choi, G
DOI：
10.1073/pnas.0407107101
发表时间：
2004-11-16
影响因子：
11.1
作者：
Monte, E;Tepperman, JM;Quail, PH
通讯作者：
Quail, PH