Effects of thermal manipulation of eggs on the response of jejunal mucosae to posthatch chronic heat stress in broiler chickens.
Effects of thermal manipulation of eggs on the response of jejunal mucosae to posthatch chronic heat stress in broiler chickens.
复制标题
鸡蛋热操作对肉鸡空肠粘膜对孵化后慢性热应激反应的影响。
DOI：
10.1016/j.psj.2019.12.038
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发表时间：
2020-05
期刊：
影响因子：
4.4
通讯作者：
Mohammad Saleh KM
中科院分区：
文献类型：
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作者：
Al-Zghoul MB;Mohammad Saleh KM
In this study, the aim was to investigate effects of chronic heat stress (CHS) on the mRNA levels of proinflammatory cytokines (interleukin [IL]-6, IL-8, IL-1β, and tumor necrosis factor alpha [TNF-α]), toll-like receptors (TLR2 and TLR4), heat shock proteins (Hsp70, heat shock transcription factor [HSF]-1, and HSF3) and antioxidant enzymes (catalase, glutathione peroxidase, NADPH oxidase, and superoxide-dismutase) in the jejunal mucosae of broiler chickens subjected to thermal manipulation (TM) during embryogenesis. TM was carried out at 39°C and 65% relative humidity (RH) for 18 h daily from embryonic days 10 to 18. Control group was incubated at 37.8°C and 56% RH. CHS was induced by raising the temperature to 35°C for 7 D throughout posthatch days 28 to 35. On post-hatch-day 28 (day zero of CHS) and after 1, 3, 5, and 7 D of CHS, the jejunal mucosae were collected from both groups to evaluate the mRNA levels by real-time reverse transcription-PCR analysis. On day zero of CHS, the mRNA levels of antioxidant enzymes, TLRs, HSF3, IL-1β, and TNF-α were not significantly different between TM and control groups, while the levels of IL-6, IL-8, and HSF1 were lower and the level of Hsp70 was higher in TM. However, during CHS, the mRNA levels of antioxidant enzymes, IL-1β, TNF-α, TLR4, and HSF1 were significantly lower in TM than in controls, while the levels of TLR2 and IL-8 were significantly higher in TM than in controls. In addition, TM led to significant increase of mRNA levels of IL-6 and HSF3 after 1 D and Hsp70 after 3 D of CHS and to significant decrease of mRNA levels of IL-6 after 3 and 5 D, HSF3 after 7 D, and Hsp70 after 5 D of CHS. Results of this study suggest that TM led to altered posthatch antioxidant, immunological, and Hsp response to CHS in the jejunal mucosae of broiler chickens, probably indicating that TM may mitigate the adverse effects of CHS.
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影响因子：
0.8
作者：
Abbas, Ghulam;Mahmood, Sultan;Nawaz, Haq
通讯作者：
Nawaz, Haq
影响因子：
4.4
作者：
Al-Zghoul, M. B.;Sukker, H.;Ababneh, M. M.
通讯作者：
Ababneh, M. M.
影响因子：
2.4
作者：
Al-Zhgoul, Mohammad-Borhan;Dalab, Abd Elhafeed S.;Ismail, Zuhair Bani
通讯作者：
Ismail, Zuhair Bani
影响因子：
5.4
作者：
Bosch, I;Xhaja, K;Rothman, AL
通讯作者：
Rothman, AL
DOI：
10.1046/j.1439-0396.2000.00223.x
发表时间：
2000-03-01
期刊：
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION-ZEITSCHRIFT FUR TIERPHYSIOLOGIE TIERERNAHRUNG UND FUTTERMITTELKUNDE
影响因子：
--
作者：
Hai, L;Rong, D;Zhang, ZY
通讯作者：
Zhang, ZY