Disseminated Mycobacterium avium complex: correlation between blood and tissue burden.
Disseminated Mycobacterium avium complex: correlation between blood and tissue burden.
复制标题
播散性鸟分枝杆菌复合体：血液和组织负荷之间的相关性。
DOI：
--
复制
发表时间：
1996
影响因子：
6.4
通讯作者：
D. Havlir
中科院分区：
文献类型：
--
作者：
F. Torriani;C. Behling;McCutchan Ja;R. Haubrich;D. Havlir
为探讨禽分枝杆菌复合体(MAC)在血液和组织中含量的关系，对10例经MAC菌血症治疗的艾滋病患者尸检时的血样和7个器官的组织标本进行了组织病理学检查和MAC定量培养。血和组织培养3例MAC阴性，7例阳性。血和组织中MAC集落形成单位的数量高度相关。网状内皮器中MAC浓度最高，肠系膜淋巴结最高达6.9log10CFU/g，脾最高达6.8log10CFU/g。组织病理学结果与定量培养结果平行，并与MAC通过淋巴管通过胃肠道进入，随后是血源性播散相一致。
To determine the relationship between levels of Mycobacterium avium complex (MAC) in blood and tissues, histopathologic examination and quantitative MAC cultures were done on blood samples and tissue samples of 7 organs at autopsy of 10 AIDS patients who had been treated for MAC bacteremia. Blood and tissue cultures were negative for MAC for 3 of the patients and positive for 7. The numbers of MAC colony-forming units in the blood and tissues were highly correlated. The highest concentrations of MAC were observed in the reticuloendothelial organs, with a maximum of 6.9 log10 cfu/g in mesenteric lymph nodes and 6.8 log10 cfu/g in spleen. Histopathologic findings paralleled quantitative cultures and were consistent with entry of MAC via lymphatics through the gastrointestinal tract, followed by hematogenous dissemination.
患有获得性细胞介导免疫缺陷的同性恋男性中传播的鸟胞内分枝杆菌感染：两例病例的组织学和免疫学研究。
影响因子：
3.5
作者：
Sohn,CC;Schroff,RW;Kliewer,KE;Lebel,DM;Fligiel,S
通讯作者：
Fligiel,S