BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease
BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease
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BHBA 治疗通过针对阿尔茨海默病转基因小鼠模型的多效机制来改善认知功能
DOI:
10.1096/fj.201901984r
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发表时间:
2019-12
期刊:
影响因子:
--
通讯作者:
Wei Wang
中科院分区:
文献类型:
--
作者:
Yancheng Wu;Yuhong Gong;Yongxin Luan;Yang Li;Juxiong Liu;Zitong Yue;Boyu Yuan;Jingxuan Sun;Changxin Xie;Lijuan Li;Junli Zhen;Xinxin Jin;Yan Zheng;Xiaomin Wang;Liwei Xie;Wei Wang
Accumulation of amyloid β (Aβ) peptide, inflammation, and oxidative stress contribute to Alzheimer's disease (AD) and trigger complex pathogenesis. The ketone body β‐hydroxybutyrate (BHBA) is an endogenous metabolic intermediate that protects against stro
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影响因子:
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DOI:
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