Functional connectivity in apathy of late-life depression: a preliminary study.

Functional connectivity in apathy of late-life depression: a preliminary study.
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DOI:
10.1016/j.jad.2012.11.023
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发表时间:
2013-07
影响因子:
6.6
通讯作者:
Gunning, Faith M.
Gunning, Faith M.
中科院分区:
医学2区
文献类型:
--
作者:
Alexopoulos, George S.;Hoptman, Matthew J.;Yuen, Genevieve;Kanellopoulos, Dora;Seirup, Joanna K.;Lim, Kelvin O.;Gunning, Faith M.

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冷漠在老年抑郁症中很常见,并且与残疾和抗抑郁药反应不佳有关。本研究探讨了伏隔核(NAcc)和背侧前扣带回(dACC)与其他结构的静息功能连接(FC)是否能够区分冷漠抑郁的老年患者与非冷漠抑郁患者以及正常受试者。
Apathy is common in late-life depression and is associated with disability and poor antidepressant response. This study examined whether resting functional connectivity (FC) of the nucleus accumbens (NAcc) and the dorsal anterior cingulate (dACC) with other structures can distinguish apathetic depressed older patients from nonapathetic depressed patients and normal subjects.
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