Emotional imagery: assessing pleasure and arousal in the brain's reward circuitry.
Emotional imagery: assessing pleasure and arousal in the brain's reward circuitry.
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DOI：
10.1002/hbm.20948
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发表时间：
2010-09
影响因子：
4.8
通讯作者：
Bradley, Margaret M.
中科院分区：
文献类型：
--
作者：
Costa, Vincent D.;Lang, Peter J.;Sabatinelli, Dean;Versace, Francesco;Bradley, Margaret M.
关键词：
对情绪感知和学习的研究表明，食欲线索会激活伏隔核（NAc）和内侧前额叶皮层（mPFC），而杏仁核的活动则受到食欲和厌恶线索的情绪强度的调节。本研究旨在确定在叙事性情绪想象过程中这些区域之间的功能激活和连接模式。利用事件相关的功能性磁共振成像（fMRI），我们研究了当参与者生动地想象愉快、中性和不愉快的场景时这些结构的激活情况。结果表明，愉快的想象选择性地激活伏隔核和内侧前额叶皮层，而杏仁核在愉快和不愉快的想象过程中激活都增强。伏隔核和内侧前额叶皮层的活动分别与想象场景的愉悦程度评分相关，而杏仁核的活动则与情绪唤醒程度评分相关。在整个想象过程中，无论享乐内容如何，伏隔核和内侧前额叶皮层之间都存在明显的功能连接，而杏仁核与伏隔核和内侧前额叶皮层的相关激活则特定于想象愉快的场景。这些发现有力地证明了愉悦的文本驱动想象会激活一个核心的食欲回路，包括伏隔核、内侧前额叶皮层和杏仁核。
Research on emotional perception and learning indicates appetitive cues engage nucleus accumbens (NAc) and medial prefrontal cortex (mPFC), whereas amygdala activity is modulated by the emotional intensity of appetitive and aversive cues. This study sought to determine patterns of functional activation and connectivity among these regions during narrative emotional imagery. Using event-related fMRI, we investigate activation of these structures when participants vividly imagine pleasant, neutral, and unpleasant scenes. Results indicate that pleasant imagery selectively activates NAc and mPFC, whereas amygdala activation was enhanced during both pleasant and unpleasant imagery. NAc and mPFC activity were each correlated with the rated pleasure of the imagined scenes, while amygdala activity was correlated with rated emotional arousal. Functional connectivity of NAc and mPFC was evident throughout imagery, regardless of hedonic content, while correlated activation of the amygdala with NAc and mPFC was specific to imagining pleasant scenes. These findings provide strong evidence that pleasurable text-driven imagery engages a core appetitive circuit, including NAc, mPFC, and the amygdala.
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影响因子：
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作者：
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通讯作者：
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