PhyreStorm: A Web Server for Fast Structural Searches Against the PDB.
PhyreStorm: A Web Server for Fast Structural Searches Against the PDB.
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DOI：
10.1016/j.jmb.2015.10.017
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发表时间：
2016-02-22
影响因子：
5.6
通讯作者：
Kelley LA
中科院分区：
文献类型：
--
作者：
Mezulis S;Sternberg MJE;Kelley LA
The identification of structurally similar proteins can provide a range of biological insights, and accordingly, the alignment of a query protein to a database of experimentally determined protein structures is a technique commonly used in the fields of structural and evolutionary biology. The PhyreStorm Web server has been designed to provide comprehensive, up-to-date and rapid structural comparisons against the Protein Data Bank (PDB) combined with a rich and intuitive user interface. It is intended that this facility will enable biologists inexpert in bioinformatics access to a powerful tool for exploring protein structure relationships beyond what can be achieved by sequence analysis alone. By partitioning the PDB into similar structures, PhyreStorm is able to quickly discard the majority of structures that cannot possibly align well to a query protein, reducing the number of alignments required by an order of magnitude. PhyreStorm is capable of finding 93 ± 2% of all highly similar (TM-score > 0.7) structures in the PDB for each query structure, usually in less than 60 s. PhyreStorm is available at http://www.sbg.bio.ic.ac.uk/phyrestorm/.
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影响因子：
14.8
作者：
Kelley LA;Mezulis S;Yates CM;Wass MN;Sternberg MJ
通讯作者：
Sternberg MJ
DOI：
10.1093/bioinformatics/btq572
发表时间：
2010-12-01
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Prlic A;Bliven S;Rose PW;Bluhm WF;Bizon C;Godzik A;Bourne PE
通讯作者：
Bourne PE
DOI：
10.1126/science.1260031
发表时间：
2015-07-17
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Chang YG;Cohen SE;Phong C;Myers WK;Kim YI;Tseng R;Lin J;Zhang L;Boyd JS;Lee Y;Kang S;Lee D;Li S;Britt RD;Rust MJ;Golden SS;LiWang A
通讯作者：
LiWang A
影响因子：
2.9
作者：
Zhang, Y;Skolnick, J
通讯作者：
Skolnick, J
影响因子：
4.8
作者：
Kim, Henna;Youn, Suk-Jun;Choi, Byong-Seok
通讯作者：
Choi, Byong-Seok