Development of acromegaly during treatment of hyperprolactinemia with bromocriptine: an unusual acidophil stem cell adenoma.
Development of acromegaly during treatment of hyperprolactinemia with bromocriptine: an unusual acidophil stem cell adenoma.
复制标题
用溴隐亭治疗高催乳素血症期间出现肢端肥大症：一种不寻常的嗜酸性干细胞腺瘤。
DOI：
10.1210/jcem.81.12.8954064
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
P. Belchetz
中科院分区：
文献类型：
--
作者：
M. Page;L. Bridges;J. Barth;A. McNichol;P. Belchetz
我们介绍了一名具有 20 年闭经史、垂体瘤、PRL 水平升高且最初检测不到 GH 的患者的临床详细信息。溴隐亭未能完全抑制PRL，并且没有肿瘤缩小。开始溴隐亭治疗后 7 个月内，患者出现肢端肥大症的临床和生化体征。在手术中，干细胞腺瘤被切除。讨论了溴隐亭导致该患者出现肢端肥大症的机制。
We present clinical details of a patient with a 20-yr history of amennorhea, a pituitary tumor, elevated PRL levels, and initially undetectable GH. Bromocriptine failed to fully suppress PRL, and there was no tumor shrinkage. Within 7 months of starting bromocriptine treatment, the patient developed clinical and biochemical signs of acromegaly. At surgery, a stem cell adenoma was excised. The mechanisms by which bromocriptine may have resulted in the development of acromegaly in this patient are discussed.
大鼠慢性高催乳素血症导致结节漏斗多巴胺能功能下降。
影响因子：
4.8
作者：
Sarkar,DK;Gottschall,PE;Meites,J
通讯作者：
Meites,J
DOI：
10.1073/pnas.79.24.7659
发表时间：
1982-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
EVANS, RM;BIRNBERG, NC;ROSENFELD, MG
通讯作者：
ROSENFELD, MG