Translational Systems Pharmacology Studies in Pregnant Women.

Translational Systems Pharmacology Studies in Pregnant Women.
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DOI:
10.1002/psp4.12269
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发表时间:
2018-03
期刊:
CPT: pharmacometrics & systems pharmacology
影响因子:
--
通讯作者:
Haas DM
Haas DM
中科院分区:
其他
文献类型:
--
作者:
Quinney SK;Gullapelli R;Haas DM

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Pregnancy involves rapid physiological adaptation and complex interplay between mother and fetus. New analytic technologies provide large amounts of genomic, proteomic, and metabolomics data. The integration of these data through bioinformatics, statistical, and systems pharmacology techniques can improve our understanding of the mechanisms of normal maternal physiologic changes and fetal development. New insights into the mechanisms of pregnancy‐related disorders, such as preterm birth (PTB), may lead to the development of new therapeutic interventions and novel biomarkers.
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