Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting.
Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting.
复制标题
DOI：
10.21470/1678-9741-2021-0278
复制
发表时间：
2023-02-10
影响因子：
1.3
通讯作者：
Kalay, Nihat
中科院分区：
文献类型：
--
作者：
Yilmaz, Yucel;Kelesoglu, Saban;Elcik, Deniz;Ozmen, Rifat;Kalay, Nihat
关键词：
我们研究了新定义的全身免疫炎症指数与冠状动脉搭桥术患者新发房颤的关系。这项研究包括392例接受冠状动脉旁路移植术的患者。我们将参与者分为两组，有和没有新发心房颤动。在冠状动脉旁路移植术之前，我们评估了患者的血液样本，包括全身免疫炎症指数和其他实验室参数。我们将全身免疫炎症指数积分公式化为血小板×中性粒细胞/淋巴细胞计数。结果显示，在392例随访患者中，有80例（20.4%）发生了新发心房颤动。这些患者的全身免疫炎症指数、中性粒细胞/淋巴细胞比值和c反应蛋白水平均高于未发生新发房颤的患者（P<0.001， P<0.001， P=0.010）。在受试者工作特征曲线分析中，全身免疫-炎症指数> 712.8水平预测新发房颤的敏感性为85%，特异性为61.2%（曲线下面积0.781,95%可信区间0.727 ~ 0.835，P<0.001）。综上所述，系统性免疫炎症指数作为一种新的炎症指标，可作为预测冠状动脉搭桥术后房颤发生的决定性指标。
We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. This study included 392 patients who underwent coronary artery bypass grafting. We divided the participants into two groups as those with and without new-onset atrial fibrillation. Prior to coronary artery bypass grafting, we evaluated blood samples, including systemic immune-inflammation index, and other laboratory parameters of the patients. We formulized the systemic immune-inflammation index score as platelet × neutrophil/lymphocyte counts. The findings revealed that new-onset atrial fibrillation occurred in 80 (20.4%) of 392 patients during follow-ups. Such patients had higher systemic immune-inflammation index, neutrophil/lymphocyte ratio, and C-reactive protein levels than those who did not develop new-onset atrial fibrillation (P<0.001, P<0.001, P=0.010, respectively). In receiver operating characteristic curve analysis, systemic immune-inflammation index levels > 712.8 predicted new-onset atrial fibrillation with a sensitivity of 85% and a specificity of 61.2% (area under the curve: 0.781, 95% confidence interval: 0.727-0.835; P<0.001). Overall, systemic immune-inflammation index, a novel inflammatory marker, may be used as a decisive marker to predict the development of atrial fibrillation following coronary artery bypass grafting.
登录
查看更多内容
影响因子：
1.3
作者：
Uysal D;Aksoy F;Ibrişim E
通讯作者：
Ibrişim E
影响因子：
3.5
作者：
Scott L Jr;Li N;Dobrev D
通讯作者：
Dobrev D
影响因子：
6.1
作者：
Cosio, Francisco G.;Aliot, Etienne;Crijns, Harry
通讯作者：
Crijns, Harry
影响因子：
11.5
作者：
Hu, Bo;Yang, Xin-Rong;Fan, Jia
通讯作者：
Fan, Jia
DOI：
10.1046/j.1365-2710.2002.00383.x
发表时间：
2002-02-01
影响因子：
2
作者：
Thompson, AE;Hirsch, GM;Pearson, GJ
通讯作者：
Pearson, GJ