COVID-19 PICU guidelines: for high- and limited-resource settings.
COVID-19 PICU guidelines: for high- and limited-resource settings.
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DOI：
10.1038/s41390-020-1053-9
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发表时间：
2020-11
影响因子：
3.6
通讯作者：
Carcillo J
中科院分区：
文献类型：
--
作者：
Kache S;Chisti MJ;Gumbo F;Mupere E;Zhi X;Nallasamy K;Nakagawa S;Lee JH;Di Nardo M;de la Oliva P;Katyal C;Anand KJS;de Souza DC;Lanziotti VS;Carcillo J
受新冠肺炎大流行影响的儿童少于成人，临床表现与成人不同。有些儿童，特别是那些患有急性或慢性合并症的儿童，很可能发展为危重疾病。最近，一种多系统炎症综合征（MIS-C）在儿童中被描述，其中一些患者需要在儿科ICU治疗。成立了一个国际合作组织，审查现有证据并制定以证据为基础的护理SARS-CoV-2感染重症儿童的指南。在缺乏证据的地方，这些差距被以协商一致为基础的准则所取代。这一过程产生了44项与出现呼吸窘迫或衰竭、败血症或感染性休克、心肺骤停、misc、需要辅助治疗或体外膜肺栓塞的儿童COVID-19患者相关的建议。还描述了解释儿童中较轻疾病模式的证据以及使用重新使用的抗病毒药物、抗炎或抗血栓治疗的可能性。由于很少有登记机构在全球范围内收集这一数据，因此包括了世界不同地区儿童SARS-CoV-2感染的简要摘要。这些指南旨在协调世界各地COVID-19重症患儿接受重症监护的标准和战略。在本文发表时，这是管理感染SARS-CoV-2的危重儿童的最新证据。参考这些指南可以降低受COVID-19及其后遗症影响的儿童的发病率和潜在死亡率。这些指导方针既适用于高资源设置，也适用于有限资源设置。
Fewer children than adults have been affected by the COVID-19 pandemic, and the clinical manifestations are distinct from those of adults. Some children particularly those with acute or chronic co-morbidities are likely to develop critical illness. Recently, a multisystem inflammatory syndrome (MIS-C) has been described in children with some of these patients requiring care in the pediatric ICU. An international collaboration was formed to review the available evidence and develop evidence-based guidelines for the care of critically ill children with SARS-CoV-2 infection. Where the evidence was lacking, those gaps were replaced with consensus-based guidelines. This process has generated 44 recommendations related to pediatric COVID-19 patients presenting with respiratory distress or failure, sepsis or septic shock, cardiopulmonary arrest, MIS-C, those requiring adjuvant therapies, or ECMO. Evidence to explain the milder disease patterns in children and the potential to use repurposed anti-viral drugs, anti-inflammatory or anti-thrombotic therapies are also described. Brief summaries of pediatric SARS-CoV-2 infection in different regions of the world are included since few registries are capturing this data globally. These guidelines seek to harmonize the standards and strategies for intensive care that critically ill children with COVID-19 receive across the world. At the time of publication, this is the latest evidence for managing critically ill children infected with SARS-CoV-2. Referring to these guidelines can decrease the morbidity and potentially the mortality of children effected by COVID-19 and its sequalae. These guidelines can be adapted to both high- and limited-resource settings.
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DOI：
10.15557/pimr.2020.0003
发表时间：
2020-01-01
影响因子：
3.6
作者：
通讯作者：
--
DOI：
10.1007/s00392-020-01766-y
发表时间：
2021-07
期刊：
Clinical research in cardiology : official journal of the German Cardiac Society
影响因子：
--
作者：
Ameri P;Inciardi RM;Di Pasquale M;Agostoni P;Bellasi A;Camporotondo R;Canale C;Carubelli V;Carugo S;Catagnano F;Danzi G;Dalla Vecchia L;Giovinazzo S;Gnecchi M;Guazzi M;Iorio A;La Rovere MT;Leonardi S;Maccagni G;Mapelli M;Margonato D;Merlo M;Monzo L;Mortara A;Nuzzi V;Piepoli M;Porto I;Pozzi A;Provenzale G;Sarullo F;Sinagra G;Tedino C;Tomasoni D;Volterrani M;Zaccone G;Lombardi CM;Senni M;Metra M
通讯作者：
Metra M
影响因子：
8.8
作者：
de Jager, Pauline;Burgerhof, Johannes G. M.;Kneyber, Martin C. J.
通讯作者：
Kneyber, Martin C. J.
DOI：
10.1007/s10096-004-1271-9
发表时间：
2005-01
期刊：
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
影响因子：
--
作者：
Cheng Y;Wong R;Soo YO;Wong WS;Lee CK;Ng MH;Chan P;Wong KC;Leung CB;Cheng G
通讯作者：
Cheng G
影响因子：
1.4
作者：
Berenise Gamez-Gonzalez, Luisa;Moribe-Quintero, Isabel;Yamazaki-Nakashimada, Marco
通讯作者：
Yamazaki-Nakashimada, Marco