[Effects of pharyngeal electrical stimulation on the swallowing reflex and its possible clinical application].
[Effects of pharyngeal electrical stimulation on the swallowing reflex and its possible clinical application].
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咽部电刺激对吞咽反射的影响及其临床应用[J].
DOI：
10.5692/clinicalneurol.52.1192
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
M. Inoue
中科院分区：
文献类型：
--
作者：
M. Inoue
本研究测试了电刺激是否会增加人类自愿重复吞咽的次数，以及外周输入的总和是否会增加吞咽次数。此外，启动自愿和非自愿吞咽的潜力进行了比较，咀嚼行为的电刺激诱发的吞咽启动的影响进行了评估。中咽部和下咽部刺激的易化效应均远大于中咽部刺激。脉冲持续时间越长，吞咽次数越多，提示外周输入在时间和空间上叠加到吞咽中枢。受试者之间的吞咽次数差异很大。反射诱发的吞咽次数（即，通过咽部刺激的吞咽（不自主吞咽）也变化很大，并且自主吞咽和不自主吞咽之间的吞咽次数存在显著的线性相关性，这表明吞咽中枢模式发生器是两种神经网络的共同组成部分，因此负责个体间的变化。咀嚼强烈抑制吞咽的开始。虽然咀嚼行为如何调节吞咽功能尚需进一步研究，但这些数据表明咀嚼中枢和吞咽中枢之间存在功能性相互作用。
The present study tested whether electrical stimulation increases the number of voluntary repetitive swallows in humans and if summation of peripheral inputs increases the number of swallows. In addition, the potential of initiating both voluntary and involuntary swallowing was compared and the effect of chewing behaviors on the initiation of swallowing evoked by the electrical stimulation was evaluated. Facilitatory effect of both the mid- and hypo-pharyngeal stimulation was much larger than that of mid-pharyngeal stimulation. The longer the pulse duration was, the larger the number of swallows was, suggesting temporal and spatial summation of peripheral inputs into the swallowing center. There was a wide variation in the number of swallows among subjects. The number of reflexively evoked swallowing (i.e., involuntary swallow) by pharyngeal stimulation also varied greatly, and there was a significant linear correlation in the number of swallows between voluntary and involuntary swallowing, which suggests that the swallowing central pattern generator is a common component of both neuronal networks and therefore is responsible for inter-individual variations. The chewing strongly inhibited the initiation of swallows. Although it should be clarified how the chewing behaviors modulate swallowing function, these data suggest the functional interaction between chewing and swallowing centers.
两个皮质咀嚼区在调节大鼠吞咽反射中的差异参与
影响因子：
2.5
作者：
T Tsujimura;K Tsuji;S Ariyasinghe;T Fukuhara;A Yamada;H Hayashi;Y Nakamura;K Iwata;M Inoue
通讯作者：
M Inoue
水和盐溶液刺激喉咽对人类自主吞咽的影响：喉咽粘膜水受体的特征。
DOI：
--
发表时间：
2010
期刊：
Chemical Senses 35
影响因子：
--
作者：
Yasuyuki Kitada;Rika Yahagi;Kazuhisa Okuda-Akabane
通讯作者：
Kazuhisa Okuda-Akabane