Role of late photons in diffuse optical imaging.

Role of late photons in diffuse optical imaging.
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晚光子在漫射光学成像中的作用。

DOI:
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发表时间:
2020
期刊:
影响因子:
3.8
通讯作者:
D. Faccio
D. Faccio
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
J. Radford;A. Lyons;F. Tonolini;D. Faccio

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通过混浊介质(例如有机组织)成像的能力对于生物和医学成像是非常有吸引力的前景。然而,这是具有挑战性的,由于组织的高度散射特性,这扰乱了图像信息。到达检测器的最早光子通常与弹道传输相关联,而较晚的光子由于多个独立的散射事件而与复杂路径相关联,因此通常被认为对最终图像形成过程是有害的。在这项工作中,我们报告的重要性,这些高度扩散,“晚”光子计算时间的飞行扩散光学成像。在厚散射材料,>80运输平均自由程,我们提供的证据表明,包括后期光子在逆检索提高图像重建质量。我们还表明,晚光子单独有足够的信息来检索图像的质量类似的早期光子门控数据。这一结果强调了充分的时间分辨成像技术在强扩散制度的重要性。
The ability to image through turbid media, such as organic tissues, is a highly attractive prospect for biological and medical imaging. This is challenging, however, due to the highly scattering properties of tissues which scramble the image information. The earliest photons that arrive at the detector are often associated with ballistic transmission, whilst the later photons are associated with complex paths due to multiple independent scattering events and are therefore typically considered to be detrimental to the final image formation process. In this work, we report on the importance of these highly diffuse, "late" photons for computational time-of-flight diffuse optical imaging. In thick scattering materials, >80 transport mean free paths, we provide evidence that including late photons in the inverse retrieval enhances the image reconstruction quality. We also show that the late photons alone have sufficient information to retrieve images of a similar quality to early photon gated data. This result emphasises the importance in the strongly diffusive regime of fully time-resolved imaging techniques.
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