Stimulus Encoding and Feature Extraction by Multiple Sensory Neurons
Stimulus Encoding and Feature Extraction by Multiple Sensory Neurons
复制标题
多个感觉神经元的刺激编码和特征提取
作者：
R. Krahe;Gabriel Kreiman;F. Gabbiani;C. Koch;W. Metzner
地形感觉图中的相邻细胞可能会将类似的信息传递给下一个更高级别的处理。附近神经元群的信息传输与单个细胞的性能相比如何，对于理解神经系统的功能来说是一个非常重要的问题。为了解决这个问题，我们量化的刺激编码和特征提取性能的同时记录在弱电鱼后脑的电感觉锥体细胞对。这些细胞构成了第一中枢神经阶段的输出神经元。使用随机幅度调制（RAM）的模仿鱼自己的电场在行为相关的频带内，我们发现，锥体细胞重叠的感受野表现出强烈的刺激诱导的相关性。为了量化RAM时间过程的编码，我们估计刺激同时记录的尖峰列车，并发现显着改善单穗列车。刺激重建的质量，但是，仍然不如单初级感觉传入测量的。在特征提取的分析中，我们发现，与孤立的尖峰甚至单个细胞的尖峰爆发相比，在几毫秒的时间窗口内重合的锥体细胞对的尖峰在检测刺激的上行和下行方面表现得更好。因此，重合尖峰可以被认为是“分布式突发”。我们的研究结果表明，初级感觉传入的刺激编码转化为特征提取在下一个处理阶段。在那里，刺激诱导的同步活动可以提高从刺激中提取行为相关特征的能力。
Neighboring cells in topographical sensory maps may transmit similar information to the next higher level of processing. How information transmission by groups of nearby neurons compares with the performance of single cells is a very important question for understanding the functioning of the nervous system. To tackle this problem, we quantified stimulus-encoding and feature extraction performance by pairs of simultaneously recorded electrosensory pyramidal cells in the hindbrain of weakly electric fish. These cells constitute the output neurons of the first central nervous stage of electrosensory processing. Using random amplitude modulations (RAMs) of a mimic of the fish's own electric field within behaviorally relevant frequency bands, we found that pyramidal cells with overlapping receptive fields exhibit strong stimulus-induced correlations. To quantify the encoding of the RAM time course, we estimated the stimuli from simultaneously recorded spike trains and found significant improvements over single spike trains. The quality of stimulus reconstruction, however, was still inferior to the one measured for single primary sensory afferents. In an analysis of feature extraction, we found that spikes of pyramidal cell pairs coinciding within a time window of a few milliseconds performed significantly better at detecting upstrokes and downstrokes of the stimulus compared with isolated spikes and even spike bursts of single cells. Coincident spikes can thus be considered “distributed bursts.” Our results suggest that stimulus encoding by primary sensory afferents is transformed into feature extraction at the next processing stage. There, stimulus-induced coincident activity can improve the extraction of behaviorally relevant features from the stimulus.
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猫视觉皮层神经元对之间相关放电的感受野图。
影响因子：
2.5
作者：
Ghose,GM;Ohzawa,I;Freeman,RD
通讯作者：
Freeman,RD
DOI：
10.1073/pnas.93.2.609
发表时间：
1996-01-23
影响因子：
11.1
作者：
Meister, M
通讯作者：
Meister, M
影响因子：
2.5
作者：
Bastian, J;Nguyenkim, J
通讯作者：
Nguyenkim, J
板球尾部系统中四个已识别的初级感觉中间神经元动态编码的信息论分析。
DOI：
10.1152/jn.1996.75.4.1345
发表时间：
1996
期刊：
Journal of neurophysiology.
影响因子：
--
作者：
Theunissen,F;Roddey,JC;Stufflebeam,S;Clague,H;Miller,JP
通讯作者：
Miller,JP