Examining the central and peripheral processes of written word production through meta-analysis.
Examining the central and peripheral processes of written word production through meta-analysis.
复制标题
DOI：
10.3389/fpsyg.2011.00239
复制
发表时间：
2011
影响因子：
3.8
通讯作者：
Rapp B
中科院分区：
文献类型：
--
作者：
Purcell JJ;Turkeltaub PE;Eden GF;Rapp B
产生书面文字需要“中央”认知过程（如拼写长期记忆和工作记忆）以及更多的外围过程，这些过程负责产生以各种格式（手写，打字等）产生书面文字所需的运动动作。近年来，各种功能性神经影像学研究已经检查了书面文字产生的中枢和外周过程的神经基质。本研究通过应用激活似然估计（ALE）方法（Turkeltaub等人）首次对这些研究进行了定量荟萃分析。对于字母语言，我们确定了11项研究（共有17个实验对比），这些研究旨在隔离单词拼写的中央和/或外围过程（参与者总数= 146）。进行了3项ALE荟萃分析。一个涉及完整的17个对比;另外两个应用于子集的对比，以区分从周边过程的中央的神经基板。这些分析确定了一个与单词拼写的中枢和外围过程可靠相关的大脑区域网络。在许多重要的结果中，有一个发现是，在各项研究中，对应性最高的区域是左颞下回/梭状回和左额下回。此外，虽然角回（AG）传统上被确定为一个关键网站内的书面文字生产网络，没有一个荟萃分析发现它是一个一致的网站的激活，而是确定了一个区域只是上级/内侧的左侧AG在左后顶内沟。这些元分析和结果的讨论提供了一个有价值的基础上，未来的研究，检查书面文字生产的神经基础可以建立。
Producing written words requires “central” cognitive processes (such as orthographic long-term and working memory) as well as more peripheral processes responsible for generating the motor actions needed for producing written words in a variety of formats (handwriting, typing, etc.). In recent years, various functional neuroimaging studies have examined the neural substrates underlying the central and peripheral processes of written word production. This study provides the first quantitative meta-analysis of these studies by applying activation likelihood estimation (ALE) methods (Turkeltaub et al.,). For alphabet languages, we identified 11 studies (with a total of 17 experimental contrasts) that had been designed to isolate central and/or peripheral processes of word spelling (total number of participants = 146). Three ALE meta-analyses were carried out. One involved the complete set of 17 contrasts; two others were applied to subsets of contrasts to distinguish the neural substrates of central from peripheral processes. These analyses identified a network of brain regions reliably associated with the central and peripheral processes of word spelling. Among the many significant results, is the finding that the regions with the greatest correspondence across studies were in the left inferior temporal/fusiform gyri and left inferior frontal gyrus. Furthermore, although the angular gyrus (AG) has traditionally been identified as a key site within the written word production network, none of the meta-analyses found it to be a consistent site of activation, identifying instead a region just superior/medial to the left AG in the left posterior intraparietal sulcus. These meta-analyses and the discussion of results provide a valuable foundation upon which future studies that examine the neural basis of written word production can build.
登录
查看更多内容
神经网络对于拼写至关重要。
影响因子：
11.2
作者：
Cloutman, Lauren;Gingis, Leila;Newhart, Melissa;Davis, Cameron;Heidler-Gary, Jennifer;Crinion, Jennifer;Hillis, Argye E.
通讯作者：
Hillis, Argye E.
影响因子：
5.7
作者：
Cohen, L;Jobert, A;Dehaene, S
通讯作者：
Dehaene, S
影响因子：
64.8
作者：
CARAMAZZA, A;HILLIS, AE
通讯作者：
HILLIS, AE
影响因子：
3.4
作者：
Chialant, D;Caramazza, A
通讯作者：
Caramazza, A
影响因子：
--
作者：
ALEXANDER, MP;FISCHER, RS;FRIEDMAN, R
通讯作者：
FRIEDMAN, R