Parasitic infections: a role for C-type lectins receptors.
Parasitic infections: a role for C-type lectins receptors.
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DOI:
10.1155/2013/456352
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发表时间:
2013
影响因子:
--
通讯作者:
Rodriguez-Sosa M
中科院分区:
文献类型:
--
作者:
Vázquez-Mendoza A;Carrero JC;Rodriguez-Sosa M
Antigen-presenting cells (APCs) sense the microenvironment through several types of receptors that recognize pathogen-associated molecular patterns. In particular, C-type lectins receptors (CLRs), which are expressed by distinct subsets of dendritic cells (DCs) and macrophages (MØs), recognize and internalize specific carbohydrate antigens in a Ca2+-dependent manner. The targeting of these receptors is becoming an efficient strategy for parasite recognition. However, relatively little is known about how CLRs are involved in both pathogen recognition and the internalization of parasites. The role of CLRs in parasite infections is an area of considerable interest because this research will impact our understanding of the initiation of innate immune responses, which influences the outcome of specific immune responses. This paper attempts to summarize our understanding of the effects of parasites' interactions with CLRs.
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影响因子:
9.2
作者:
Garrido VV;Dulgerian LR;Stempin CC;Cerbán FM
通讯作者:
Cerbán FM
DOI:
10.1084/jem.20021890
发表时间:
2003-05-05
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Brown GD;Herre J;Williams DL;Willment JA;Marshall AS;Gordon S
通讯作者:
Gordon S
DOI:
10.1038/nri2569
发表时间:
2009-07
期刊:
Nature reviews. Immunology
影响因子:
--
作者:
Geijtenbeek TB;Gringhuis SI
通讯作者:
Gringhuis SI
影响因子:
1.3
作者:
Basso, W;Venturini, L;Dubey, JP
通讯作者:
Dubey, JP
影响因子:
6.4
作者:
deSchoolmeester, Matthew L.;Martinez-Pomares, Luisa;Else, Kathryn J.
通讯作者:
Else, Kathryn J.