Caffeine for the care of preterm infants in sub-Saharan Africa: a missed opportunity?
Caffeine for the care of preterm infants in sub-Saharan Africa: a missed opportunity?
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DOI：
10.1136/bmjgh-2021-007682
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发表时间：
2021-12
影响因子：
8.1
通讯作者：
Neonatal Nutrition Network (NeoNuNet)
中科院分区：
文献类型：
--
作者：
Nabwera HM;Ekhaguere OA;Kirpalani H;Burgoine K;Ezeaka CV;Otieno W;Allen SJ;Embleton ND;Neonatal Nutrition Network (NeoNuNet)
2019年，全球有240万新生儿（小于28天的婴儿）死亡。其中80%以上是早产儿（妊娠期<37周），大多数出生在低收入和中等收入国家。1早产并发症，主要是由表面活性物质缺乏引起的呼吸窘迫综合征、肺炎或早产儿呼吸暂停（AOP），现在是全球5岁以下儿童死亡的主要原因。1在缺乏有效的辅助治疗的情况下，这些疾病通常是致命的，这在撒哈拉以南非洲的新生儿病房很常见。虽然全球新生儿死亡率在过去三十年中减少了一半，但区域差异仍然很大。这些数字与世界银行和国际货币基金组织对每天生活费低于1.90美元的人口比例的估计数相关联，而大多数较贫穷的国家都在撒哈拉以南非洲。据估计，在撒哈拉以南非洲出生的婴儿死亡的可能性是在高收入国家出生的婴儿的10倍。撒哈拉非洲不太可能实现到2030年每1000例活产新生儿死亡不超过12例的全球目标。75个国家（几乎一半来自撒哈拉以南非洲）签署了“每个新生儿行动计划”，该计划具有战略性的全球和国家行动以及里程碑，以解决孕产妇和新生儿的差距。4这一雄心勃勃的承诺需要循证干预5和创新战略，以提高新生儿存活率和长期结果。
In 2019, 2.4 million neonates (infants <28 days of age) died globally. Of these, over 80% were preterm infants (<37 weeks gestation), with the majority born in low-income and middle-income countries. 1 Complications of preterm birth, largely from respiratory distress syndrome due to surfactant deficiency, pneumonia or apnoea of prematurity (AOP), are now the leading cause of under 5 mortality globally.1 These conditions are frequently fatal in the absence of effective ventilatory support which is commonplace in neonatal units across sub-Saharan Africa. Although the global neonatal mortality rate (NMR) has halved over the past three decades, significant regional disparities remain. These correlate with World Bank and International Monetary Fund estimates of the proportion of the population living on less than US$1.90 a day, with the majority of poorer countries being in sub-Saharan Africa.1 2 As the region with the highest NMR of 27 per 1000 live births, it is estimated that a baby born in in sub-Saharan Africa is 10 times more likely to die than one born in a high income country.1 Countries in sub-Saharan Africa are unlikely to meet the global target of no more than 12 newborn deaths per 1000 live births by 2030.3 In 2017, 75 countries (almost half from sub-Saharan Africa) signed up to the ‘Every Newborn Action Plan’ that has strategic global and national actions and milestones to address gaps in maternal and newborn care.4 This ambitious commitment requires evidence-based interventions5 and innovative strategies to improve neonatal survival and longer-term outcomes.
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DOI：
10.5409/wjcp.v4.i4.81
发表时间：
2015-11-08
期刊：
World journal of clinical pediatrics
影响因子：
--
作者：
Abdel-Hady, Hesham;Nasef, Nehad;Nour, Islam
通讯作者：
Nour, Islam
影响因子：
5.1
作者：
Stark, Ashley;Smith, P. Brian;Hornik, Christoph P.;Zimmerman, Kanecia O.;Hornik, Chi D.;Pradeep, Sidart;Clark, Reese H.;Benjamin, Daniel K., Jr.;Laughon, Matthew;Greenberg, Rachel G.
通讯作者：
Greenberg, Rachel G.
影响因子：
3
作者：
Ekhaguere, Osayame A.;Ayede, Adejumoke, I;Ezeaka, Chinyere, V
通讯作者：
Ezeaka, Chinyere, V
影响因子：
168.9
作者：
Bhutta, Zulfiqar A.;Das, Jai K.;Walker, Neff
通讯作者：
Walker, Neff
影响因子：
1
作者：
Schellack, Natalie;Gous, Andries G. S.;Mawela, Patience B.
通讯作者：
Mawela, Patience B.