Oncogenes and tumor-suppressing genes.
Oncogenes and tumor-suppressing genes.
复制标题
癌基因和肿瘤抑制基因。
DOI:
10.1056/nejm198803103181007
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发表时间:
1988
期刊:
影响因子:
--
通讯作者:
Weinberg,RA
中科院分区:
文献类型:
--
作者:
Friend,SH;Dryja,TP;Weinberg,RA
THE past decade has witnessed great changes in our understanding of the molecular origins of cancer. Much of this progress stems from the discovery of specific genes, the oncogenes, which are carried in the genomes of a variety of tumor cells and appear to be responsible for specifying many of the malignant traits of these cells. Laboratory work in several areas has now uncovered 30 distinct oncogenes, some of which are associated with specific tumor types.1Recently, researchers have discovered a very different class of genes that are involved in some forms of carcinogenesis. These "tumor-suppressing" genes appear to be . . .
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影响因子:
56.9
作者:
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通讯作者:
R. Sparkes;MC Sparkes;M. Wilson;JW Towner;W. Benedict;A. Murphree;J. Yunis
影响因子:
64.5
作者:
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通讯作者:
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作者:
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通讯作者:
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影响因子:
11.1
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H. Varmus
通讯作者:
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影响因子:
64.8
作者:
N. Simpson;K. Kidd;P. Goodfellow;H. McDermid;S. Myers;J. Kidd;C. Jackson;A. Duncan;L. Farrer;K. Brasch;C. Castiglione;M. Genel;J. Gertner;C. Greenberg;J. Gusella;J. A. Holden;B. White
通讯作者:
B. White