The molecular genetics of cellular oncogenes.
The molecular genetics of cellular oncogenes.
复制标题
细胞癌基因的分子遗传学。
DOI:
10.1146/annurev.ge.18.120184.003005
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发表时间:
1984
影响因子:
11.1
通讯作者:
H. Varmus
中科院分区:
文献类型:
--
作者:
H. Varmus
DEFINITIONS OF CELLULAR ONCOGENES 555 c-one's: The Proto-Oncogenic Progenitors of Retroviral Oncogenes . . . . . . . . . . . . . . . . . . . 555 Identification of Cellular Oncogenes by Functional Tests for Dominant Mutations 558 Using Genetic Rearrangements to Identify Oncogenes . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 562 Proviral insertions can activate expression oj cellular proto-oncogenes 563 Oncogenes at translocation breakpoints. . ... . . . . ..... 566 Oncogenes in amplified DNA ..... . . ...... ........ . . . ..... ........ . . . .. . . ....... ... . . . . . .. . 567 MOLECULAR PROFILES OF ACTIVATED ONCOGENES 570 Base Substitutions in Mutant ras Alleles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570 Insertionally Mutated c-myc Loci. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574 Locations oj proviruses 574 Additional mutations in proviraUy mutated loci ...... . . .... 576 Characteristics of Other Proviral Insertion Mutations in Proto-Oncogenes 578 Structural and Functional Properties of Translocation Breakpoints near Cellular Oncogenes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581 General Jeatures oj c-myc; immunoglobulin gene translocations . . . . . . . . . . . . . . . . . . . . 581 Specific examples of c-myc; Ig translocations in PC and BL lines ........ . . . . . . . . . 583 The Phi chromosome .. . .. ....... . . . . . . . ..... . .. . ... . . . . . . . . ... . . . . . . . ... .. .. .. 586 Other translocations and rearrangements in B cell tumor lines . . . . . . . . . . . . . . . . . . . . . 587 Structural Features oj Amplified Oncogenes . ...... ..... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 587 FROM c-onc TO v-onc: COLLUSION OF MUTATIONAL MECHANISMS....... 588 The Favored Model Jar Transduction of Oncogenes . .. . . 590 The Functional Significance of Diff erences Between c-onc' s and v-onc' s 592 INACTIVATION OF INTEGRATED v-onc GENES: A SAMPLER OF MUTATIONAL MECHANISMS 593
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DOI:
10.1073/pnas.80.8.2146
发表时间:
1983
影响因子:
11.1
作者:
Watson,DK;Reddy,EP;Duesberg,PH;Papas,TS
通讯作者:
Papas,TS
DOI:
10.1126/science.6344220
发表时间:
1983
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Rasheed,S;Norman,GL;Heidecker,G
通讯作者:
Heidecker,G
DOI:
10.1073/pnas.81.15.4697
发表时间:
1984
影响因子:
11.1
作者:
Shih,CK;Linial,M;Goodenow,MM;Hayward,WS
通讯作者:
Hayward,WS
影响因子:
56.9
作者:
DOOLITTLE, RF;HUNKAPILLER, MW;ANTONIADES, HN
通讯作者:
ANTONIADES, HN
影响因子:
14.9
作者:
George,DL;Scott,AF;deMartinville,B;Francke,U
通讯作者:
Francke,U