Site and Mechanism of Recurrent Pontine Infarction: A Hospital-Based Follow-Up Study.
Site and Mechanism of Recurrent Pontine Infarction: A Hospital-Based Follow-Up Study.
复制标题
脑桥梗死复发的部位和机制：基于医院的随访研究
DOI：
10.3390/brainsci12050520
复制
发表时间：
2022-04-20
期刊：
影响因子：
3.3
通讯作者：
Jiang, Yongjun
中科院分区：
文献类型：
--
作者：
Wu, Li;Li, Youfu;Ye, Zeming;Liu, Dezhi;Dai, Zheng;Zhu, Juehua;Chen, Hongbing;Li, Chenghao;Lie, Chaowei;Jiang, Yongjun
虽然脑桥梗死是后循环卒中最常见的亚型，但很少有研究关注复发性脑桥梗死。本研究旨在探讨脑桥梗死复发的部位和机制。入选急性孤立性桥脑梗死患者，并随访一年。病变的地形是由扩散加权成像。根据病变局部解剖和其他血管、心脏和实验室检查结果确定机制。共纳入562例脑桥梗死患者，其中67例患者在随访期间复发。41例复发发生在同一部位的指数桥脑梗死（41/67，61.2%）。结果表明，指数脑桥梗死的机制与复发部位显著相关（p = 0.041，OR 2.938，95% CI 1.044 - 8.268），也与复发机制显著相关（p = 0.004，OR 6.056，95% CI 1.774 - 20.679）。分支动脉粥样硬化性疾病诱发的指数脑桥梗死可能在相同部位复发并具有相同的机制。此外，如果复发发生在同一部位，其机制可能与首次卒中相同（p = 0.000）。我们的研究可以帮助医生通过预测复发的部位和机制来治疗脑桥梗死患者。
Although pontine infarction is the most common subtype of posterior circulation stroke, there has been little research focusing on recurrent pontine infarction. Our study aimed to investigate the factors associated with site and mechanism of recurrent pontine infarction. Patients with acute isolated pontine infarction were enrolled and followed up for one year. Lesion topography was determined by diffusion-weighted imaging. Mechanisms were determined based on lesion topography and other vascular, cardiologic and laboratory results. A total of 562 patients with pontine infarction were included, with 67 patients experiencing recurrence during the follow-up period. Forty-one recurrences occurred at the same site as index pontine infarction (41/67, 61.2%). Results indicated that the mechanism of index pontine infarction was significantly associated with the recurrent sites (p = 0.041, OR 2.938, 95% CI 1.044–8.268), and also with the mechanisms of recurrence (p = 0.004, OR 6.056, 95% CI 1.774–20.679). Branch atheromatous disease-induced index pontine infarction was likely to recur at the same site and with the same mechanism. Moreover, if recurrence occurred at the same site, the mechanism was probably the same as that of the index stroke (p = 0.000). Our study may help physicians treat patients with pontine infarction by predicting the site and mechanism of recurrence.
登录
查看更多内容
影响因子：
2.6
作者：
Huang, Jiehong;Qiu, Zhihua;Jiang, Yongjun
通讯作者：
Jiang, Yongjun
影响因子：
5.4
作者：
Boulanger M;Béjot Y;Rothwell PM;Touzé E
通讯作者：
Touzé E
影响因子：
6
作者：
Vemmos, KN;Spengos, K;Vassilopoulos, D
通讯作者：
Vassilopoulos, D
影响因子：
6
作者：
Kumral, E;Bay端lkem, G;Evyapan, D
通讯作者：
Evyapan, D
影响因子：
4.8
作者：
Raghuram, Karthikram;Durgam, Aditya;Singh, Ayush
通讯作者：
Singh, Ayush