Prevalence of Anxiety and Depression in Patients with Inflammatory Bowel Disease.

Prevalence of Anxiety and Depression in Patients with Inflammatory Bowel Disease.
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DOI:
10.1155/2017/6496727
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发表时间:
2017
影响因子:
2.7
通讯作者:
Bressler B
Bressler B
中科院分区:
医学4区
文献类型:
--
作者:
Byrne G;Rosenfeld G;Leung Y;Qian H;Raudzus J;Nunez C;Bressler B

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炎症性肠病(IBD)患者没有常规筛查抑郁和焦虑,尽管慢性疾病患者的患病率增加,对生活质量有负面影响。 通过回顾性图表分析评估IBD门诊患者的焦虑和抑郁患病率。使用患者健康问卷-9和广泛性焦虑症-7自我报告问卷或通过精神病学访谈诊断确定是否存在焦虑和/或抑郁。还收集了患者人口统计学、疾病特征和药物信息。多变量分析用于确定患者因素与抑郁和焦虑之间的关联。 审查了327份病历。抑郁和焦虑的发生率分别为25.8%和21.2%,其中30.3%的患者患有抑郁和/或焦虑。发现疾病活动与抑郁和/或焦虑显著相关(p = 0.01)。女性更容易焦虑(p = 0.01)。 很大一部分IBD患者患有抑郁和/或焦虑。这些精神疾病的发病率将证明在治疗这一人群的诊所进行筛查和转诊精神病治疗是合理的。患有活动性疾病的患者特别容易患焦虑和抑郁症。
Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life. Prevalence of anxiety and depression was assessed in IBD outpatients through retrospective chart review. The presence of anxiety and/or depression was determined using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 self-report questionnaires or by diagnosis through psychiatric interview. Patient demographics, disease characteristics, and medication information were also collected. Multivariable analysis was used to determine associations between patient factors and depression and anxiety. 327 patient charts were reviewed. Rates of depression and anxiety were found to be 25.8% and 21.2%, with 30.3% of patients suffering from depression and/or anxiety. Disease activity was found to be significantly associated with depression and/or anxiety (p = 0.01). Females were more likely to have anxiety (p = 0.01). A significant proportion of IBD patients suffer from depression and/or anxiety. The rates of these mental illnesses would justify screening and referral for psychiatric treatment in clinics treating this population. Patients with active disease are particularly at risk for anxiety and depression.
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