Ultrastructural analysis of the cristae ampullares in the squirrel monkey (Saimiri sciureus).
Ultrastructural analysis of the cristae ampullares in the squirrel monkey (Saimiri sciureus).
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DOI:
10.1002/cne.21827
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发表时间:
2008-11-01
影响因子:
2.5
通讯作者:
Goldberg, Jay M.
中科院分区:
文献类型:
--
作者:
Lysakowski, Anna;Goldberg, Jay M.
Type I hair cells outnumber type II hair cells (HCs) in squirrel monkey (Saimiri sciureus) cristae by a nearly 3:1 ratio. Associated with this type I HC preponderance, calyx fibers make up a much larger fraction of the afferent innervation than in rodents. To study how this affected synaptic architecture, we used disector methods to estimate various features associated with type I and type II HCs in central (CZ) and peripheral (PZ) zones of monkey cristae. Each type I HC makes, on average, 5–10 ribbon synapses with the inner face of a calyx ending. Inner-face synapses outnumber those on calyx outer faces by a 40:1 ratio. Expressed per afferent, there are, on average, 15 inner-face ribbon synapses, 0.38 outer-face ribbons and 2.6 efferent boutons on calyx-bearing endings. Calyceal invaginations per type I HC range from 19 in CZ to 3 in PZ. For type II HCs, there are many more ribbons and afferent boutons in PZ than in CZ, whereas efferent innervation is relatively uniform throughout the neuroepithelium. Despite outer-face ribbons being more numerous in chinchilla than in squirrel monkey, afferent discharge properties are similar, reinforcing the importance of inner-face ribbons in synaptic transmission. Comparisons across mammalian species suggest the prevalence of type I HCs is a primate characteristic, rather than an arboreal lifestyle adaptation. Unlike cristae, type II HCs predominate in monkey maculae. Differences in hair-cell counts may reflect the stimulus magnitudes handled by semicircular canals and otolith organs.
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影响因子:
2.5
作者:
FERNANDEZ, C;BAIRD, RA;GOLDBERG, JM
通讯作者:
GOLDBERG, JM
影响因子:
2.5
作者:
Brichta, AM;Goldberg, JM
通讯作者:
Goldberg, JM
影响因子:
2.5
作者:
Goldberg, JM;Brichta, AM
通讯作者:
Brichta, AM
影响因子:
2.5
作者:
BAIRD, RA;DESMADRYL, G;GOLDBERG, JM
通讯作者:
GOLDBERG, JM
DOI:
10.1073/pnas.0405260101
发表时间:
2004-12-21
影响因子:
11.1
作者:
Altshuler, DL;Dudley, R;McGuire, JA
通讯作者:
McGuire, JA