Biotransformation of citronellol by the basidiomycete Cystoderma carcharias in an aerated-membrane bioreactor
Biotransformation of citronellol by the basidiomycete Cystoderma carcharias in an aerated-membrane bioreactor
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曝气膜生物反应器中担子菌 Cystoderma carcharias 对香茅醇的生物转化
DOI：
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发表时间：
1999
影响因子：
5
通讯作者：
R. Berger
中科院分区：
文献类型：
--
作者：
J. Onken;R. Berger
摘要利用担子菌Cystoderma carpinas转化香茅醇，主要产物为3，7-二甲基-1，6，7-辛三醇。3，7-二甲基-6，7-环氧-1-辛醇是生物转化的重要中间产物，烯丙基二醇2，6-二甲基-2-辛烯-1，8-二醇、3，7-二甲基-5-辛烯-1，7-二醇和3，7-二甲基-7-辛烯-1，6-二醇是次要产物。首次观察到微生物形成的玫瑰氧化物，一种风味影响成分。加入0.1 mmol l−1细胞色素单加氧酶抑制剂后，主要产物的形成被抑制了70%。在疏水聚丙烯毛细管膜上曝气的生物反应器中，3，7-二甲基-1，6，7-辛三醇的形成是有效的。生产率达到150 mg l−1 day−1，产品浓度为866 mg l−1（转化率：52%）。当使用这种通风方法时，通过排气添加的挥发性基质的总损失为4.5%。
Abstract The basidiomycete Cystoderma carcharias transformed citronellol into 3,7-dimethyl-1,6,7-octanetriol as the main product. 3,7-Dimethyl-6,7-epoxy-1-octanol was identified as important intermediary product of the biotransformation, and the allylic diols 2,6-dimethyl-2-octene-1,8-diol, 3,7-dimethyl-5-octene-1,7-diol and 3,7-dimethyl-7-octene-1,6-diol were found to be minor products. Microbial formation of rose oxide, a flavour-impact component, was observed for the first time. The formation of the main products was inhibited by 70% after addition of 0.1 mmol l−1 cytochrome monooxygenase inhibitors. Formation of 3,7-dimethyl-1,6,7-octanetriol was effective in a bioreactor with aeration over a coil of a hydrophobic microporous polypropene capillary membrane. Production rates of up to 150 mg l−1 day−1 were reached and led to a product concentration of 866 mg l−1 (conversion rate: 52%). The total loss of the added volatile substrate via the exhaust air was 4.5% when this aeration method was used.
线虫真菌细胞提取物中的酶对异生化合物的代谢。
DOI：
10.1042/bj2050117
发表时间：
1982
期刊：
The Biochemical journal
影响因子：
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作者：
Wackett,LP;Gibson,DT
通讯作者：
Gibson,DT