A Three-Dimensional Cement Quantification Method for Decision Prediction of Vertebral Recompression after Vertebroplasty.

A Three-Dimensional Cement Quantification Method for Decision Prediction of Vertebral Recompression after Vertebroplasty.
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三维骨水泥定量方法用于椎体成形术后椎体再压缩的决策预测

DOI:
10.1155/2022/2330472
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发表时间:
2022
影响因子:
--
通讯作者:
Li, Zhaoyang
Li, Zhaoyang
中科院分区:
工程技术4区
文献类型:
--
作者:
Zhang, Yanming;Zhang, Tao;Ge, Xiang;Ma, Yong;Cui, Zhenduo;Wu, Shuilin;Liang, Yanqin;Zhu, Shengli;Li, Zhaoyang

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提出量化骨水泥分布的参数,提高预测椎体成形术术后并发症的准确性。对51例经皮椎体成形术(PVP)或后凸成形术(PKP)后的椎体进行生物力学分析。椎间隙分为27个部分。用总分布数(ODN)和总终板接触数(OEP)分别定义水泥占位数和水泥-终板接触数。用ODN和OEP对粘固剂的分布进行了参数估计。椎体力学参数的确定系数(R2)可以验证所提出的参数与椎体力学的相关性。ODN和OEP分别与破坏载荷(R2=0.729)和刚度(R2=0.684)有关。PVP组和PKP组的ODN、OEP、破坏载荷和刚度差异有统计学意义(P<0.05)。在所有区域参数中,前柱的区域终板接触数与椎体硬度的相关性最强(R2=0.59)。骨水泥体积和体积分数不是椎体增大的主导因素,不适合用于术后骨折风险预测。所提出的参数具有较高的椎体力学相关性,具有临床应用前景。ODN和OEP对增强椎体力学影响较大,适用于术后骨折风险预测。这些参数对翻修手术必要性的决策过程是有益的。参数化方法也有利于外科医生的术前计划。该方法对临床图像识别的发展和辅助诊断具有一定的启发意义。
Proposing parameters to quantify cement distribution and increasing accuracy for decision prediction of vertebroplasty postoperative complication. Finite element analysis was used to biomechanically assess vertebral mechanics (n = 51) after percutaneous vertebroplasty (PVP) or kyphoplasty (PKP). The vertebral space was divided into 27 portions. The numbers of cement occupied portions and numbers of cement-endplate contact portions were defined as overall distribution number (oDN) and overall endplate contact number (oEP), respectively. And cement distribution was parametrized by oDN and oEP. The determination coefficients of vertebral mechanics and parameters (R2) can validate the correlation of proposed parameters with vertebral mechanics. oDN and oEP were mainly correlated with failure load (R2 = 0.729) and stiffness (R2 = 0.684), respectively. oDN, oEP, failure load, and stiffness had obvious difference between the PVP group and the PKP group (P < 0.05). The regional endplate contact number in the front column is most correlated with vertebral stiffness (R2 = 0.59) among all regional parameters. Cement volume and volume fraction are not dominant factors of vertebral augmentation, and they are not suitable for postoperative fracture risk prediction. Proposed parameters with high correlation on vertebral mechanics are promising for clinical utility. The oDN and oEP can strongly affect augmented vertebral mechanics thus is suitable for postoperative fracture risk prediction. The parameters are beneficial for decision-making process of revision surgery necessity. Parametrized methods are also favorable for surgeon's preoperative planning. The methods can be inspirational for clinical image recognition development and auxiliary diagnosis.
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